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Table 2 Empirical results for the averages of the relative bias (r.Bias) and standard errors (SEM), standard deviation (SD), and coverage probability (CP) for the regression parameters and variance parameter of the log-normal frailty based on the ‘imputed-by-the-right-endpoint’ and ‘proposed’ methods when the type of regression coefficients is ‘dec’ under three types of LTF proportions (‘low’, ‘moderate’, and ‘high’)

From: Additive-multiplicative hazards regression models for interval-censored semi-competing risks data with missing intermediate events

  

Low (LTF(%)=19.4)

Moderate (LTF(%)=31.4)

High (LTF(%)=43.5)

Parameter

True value

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

  

Imputed-by-the-right-endpoint method

α 01

0.01

36.6

15548

14973

93.8

-110.5

15890

15137

94.2

-97.0

15327

15425

94.6

α 02

0.02

-8.8

23990

22697

96.0

2.5

23708

25122

97.0

44.4

29732

28452

95.2

α 03

0.01

400.1

27926

26768

95.8

9.1

18791

17136

93.8

-80.3

14385

13500

93.6

α 12

0.01

100.0

27898

26371

94.6

199.2

28271

25833

92.8

172.0

29132

26387

93.8

α 32

0.01

274.6

66261

56538

93.6

121.0

35562

33829

94.4

125.5

29879

26193

94.2

β 01

0.004

-6.6

99

97

90.0

-8.7

89

96

93.4

-6.3

95

97

95.2

β 02

0.008

-0.9

137

139

94.0

-2.8

129

140

95.8

-0.3

143

149

96.0

β 03

0.004

-2.8

96

98

93.0

-5.7

121

116

91.0

-9.5

142

144

94.4

β 12

0.004

6.4

120

125

97.2

6.2

120

127

98.4

5.8

124

125

96.8

β 32

0.004

0.6

234

218

96.8

7.6

204

188

96.4

9.5

177

169

95.0

σ 2

0.01

631.4

7287

8545

97.6

705.2

6851

7982

96.2

714.8

7217

7540

90.4

  

Proposed method

α 01

0.01

21.6

15586

15134

94.0

-56.8

16268

15285

94.0

-92.4

15530

15487

94.2

α 02

0.02

-0.6

24316

22833

95.8

-18.9

24116

25162

96.6

104.0

30008

28458

95.0

α 03

0.01

337.6

27943

26924

95.4

-9.4

18629

17265

94.0

-83.6

14279

13600

94.2

α 12

0.01

43.2

27653

26452

94.6

175.4

27650

25973

93.8

102.5

28481

26251

93.2

α 32

0.01

296.4

67196

57028

93.4

140.3

36513

34261

94.8

170.0

30037

26145

93.8

β 01

0.004

-2.5

106

101

91.8

-4.5

95

99

94.6

-2.3

100

100

95.8

β 02

0.008

3.8

146

146

95.6

2.0

133

148

98.6

3.6

148

155

97.0

β 03

0.004

1.3

102

102

93.4

-0.3

124

121

94.0

-3.0

149

150

95.4

β 12

0.004

0.3

112

119

96.0

0.8

116

122

98.0

1.1

117

121

96.4

β 32

0.004

2.5

232

222

97.2

8.5

204

189

96.4

9.7

178

170

95.6

σ 2

0.01

838.4

8153

9217

94.2

852.3

7505

8446

93.8

791.2

7447

7745

89.2