Skip to main content

Table 3 Empirical results for the averages of the relative bias (r.Bias) and standard errors (SEM), standard deviation (SD), and coverage probability (CP) for the regression parameters and variance parameter of the log-normal frailty based on the ‘imputed-by-the-right-endpoint’ and ‘proposed’ methods when the type of regression coefficients is ‘acc’ under three types of LTF proportions (‘low’, ‘moderate’, and ‘high’)

From: Additive-multiplicative hazards regression models for interval-censored semi-competing risks data with missing intermediate events

  

Low (LTF(%)=22.3)

Moderate (LTF(%)=34.2)

High (LTF(%)=47.6)

Parameter

True value

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

r.Bias (%)

SD (×105)

SEM (×105)

CP (%)

  

Imputed-by-the-right-endpoint method

α 01

0.01

3.3

14848

14915

95.2

-20.8

16313

15029

92.0

-63.6

15651

15144

95.0

α 02

0.01

140.0

22910

22360

94.0

23.4

24852

24383

95.0

9.0

26169

28020

97.2

α 03

0.01

79.0

25396

26622

96.2

115.9

18132

17194

92.8

-4.9

14262

13148

93.0

α 12

0.0125

-100.2

27253

26397

94.4

10.5

30146

26715

93.0

74.9

25881

25844

95.4

α 32

0.01

479.4

59836

50929

92.0

-108.0

37118

33609

95.2

125.6

26069

25027

94.6

β 01

0.004

-11.6

89

86

89.4

-10.8

92

87

88.6

-11.3

86

87

89.2

β 02

0.004

-1.2

83

92

96.4

-3.9

89

94

95.2

-0.5

102

101

92.8

β 03

0.004

-8.6

83

85

91.4

-10.3

109

103

90.8

-11.6

149

133

89.4

β 12

0.005

3.7

133

130

96.0

2.3

125

126

96.2

3.0

131

129

96.0

β 32

0.004

0.4

197

199

95.8

6.6

172

171

95.2

3.4

139

151

96.2

σ 2

0.01

878.9

8926

8822

92.6

734.8

6989

7754

91.4

775.5

7514

7231

87.6

  

Proposed method

α 01

0.01

29.1

15161

15024

95.2

11.9

16449

15111

91.8

-99.5

15704

15169

94.8

α 02

0.01

126.2

22920

22435

93.8

-49.7

25179

24488

95.2

-34.2

26495

28218

97.4

α 03

0.01

9.4

26768

26779

95.8

98.7

17948

17287

93.8

1.1

14013

13191

93.8

α 12

0.0125

21.2

26832

26404

95.2

44.7

29934

26567

92.8

52.4

25781

25861

95.6

α 32

0.01

280.8

60729

51753

91.4

-181.5

36859

33796

95.4

173.3

26819

25056

93.2

β 01

0.004

-7.5

95

90

92.2

-6.8

95

90

90.8

-8.1

89

90

93.0

β 02

0.004

4.1

88

96

97.2

1.8

94

99

96.2

4.6

106

105

93.4

β 03

0.004

-3.9

88

89

93.6

-4.1

116

108

92.8

-6.3

154

138

90.6

β 12

0.005

-0.9

124

124

96.4

-2.0

117

122

97.0

-1.2

123

124

95.4

β 32

0.004

2.3

195

200

95.8

6.9

171

172

95.6

3.8

137

152

97.2

σ 2

0.01

999.2

9282

9124

93.0

936.4

8781

8219

88.6

873.0

8002

7404

85.6