Fig. 2

Simulated probability curves of the designation of complete or partial response or progression according to the percent change at the first reading. a Simulated probability function when the tumor burden of a 30-mm single target lesion is re-measured by another reader on the long axis. b Simulated probability function when the tumor burden of a 120-mm single target lesion is re-measured by another reader on the long axis c. Simulated probability function when a tumor burden consisting of four target lesions is re-measured by another reader on the long axis. d Simulated probability function when the tumor burden of a 30-mm single target lesion is re-measured by the same reader on the long axis. e Simulated probability function when the tumor burden of a 30-mm single target lesion is re-measured by another reader on the short axis