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Table 3 Specification of the logistic regression model used to impose missingness

From: Dealing with indeterminate outcomes in antimalarial drug efficacy trials: a comparison between complete case analysis, multiple imputation and inverse probability weighting

 Log (Odds Ratio)†Odds Ratio
Mechanism 2aMechanism 2bMechanism 2aMechanism 2b
Treatmentβ2jβ2jexp(β2j)exp(β2j)
AL (reference)0.000.001.001.00
ASAQ-0.05-0.100.950.90
DP-0.20-0.400.820.67
Transmissionβ1kβ1kexp(β1k)exp(β1k)
High (reference)0.000.001.001.00
Low-0.25-0.500.780.61
Moderate-0.15-0.300.860.74
  1. AL artemether-lumefantrine , ASAQ artesunate-amodiaquine , DP dihydroartemisinin-piperaquine
  2. †The intercept of the logistic regression (β0) was chosen by iteration to achieve the desired proportion of missingness conditional on recurrence status. This was -2.10, -0.75 and -0.11 for 10%, 30% and 45% respectively under missingness mechanism 2a, and -2.03, -0.68 and -0.02 respectively for 10%, 30% and 45% missingness under mechanism 2b.