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Table 2 Sample size balance: Differences in 16 cell sizes across 250 simulations

From: Simulation and minimization: technical advances for factorial experiments designed to optimize clinical interventions

 

Min

Max

Range

Simple randomization

11.8

27.1

15.3

Stratification with permuted blocks

14.5

23.6

9.1

MTI2

18

20.9

2.9

MTI3

18

21.4

3.4

MSB

15.2

24.4

9.2

Minimization

18.0

19.9

1.9

  1. Note. Min = Mean minimum cell size, Max = Mean maximum cell size