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Table 4 Proportion of allocations that are deterministic, fully random, or in between

From: Simulation and minimization: technical advances for factorial experiments designed to optimize clinical interventions

Cells

 
 

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

Ave. cells

SR

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

0.0%

100%

16.0

SPB

4.2%

4.3%

4.5%

4.5%

4.6%

4.7%

4.9%

5.1%

5.4%

5.4%

5.6%

6.2%

6.9%

7.4%

9.9%

18.2%

10.4

MTI2

5.9%

5.9%

5.9%

5.8%

5.4%

5.0%

4.4%

3.6%

2.9%

2.1%

1.5%

1.0%

0.6%

0.3%

0.1%

49.7%

10.6

MTI3

5.9%

5.7%

5.3%

4.8%

4.2%

3.5%

2.8%

2.1%

1.5%

1.1%

0.7%

0.4%

0.2%

0.1%

0.0%

61.6%

11.6

MSB

19.7%

16.1%

13.2%

10.8%

9.0%

7.4%

5.9%

4.4%

3.0%

2.0%

1.3%

1.1%

0.8%

0.8%

0.6%

3.9%

4.7

Min

34.0%

18.8%

13.7%

10.0%

7.1%

4.6%

2.8%

1.7%

0.9%

0.5%

0.3%

0.1%

0.1%

0.0%

0.0%

0.0%

2.7

  1. Note. 1 cell = deterministic; 16 cells = completely random. SR = simple randomization; SPB = stratification with permuted blocks; MTI = maximum tolerated imbalance; MSB = minimal sufficient balance; Min = minimization. Ave. cells = average number of cells eligible for randomization per allocation