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Table 1 Effects associated to a genetic variant

From: Assessing the effect of genetic markers on drug immunogenicity from a mechanistic model-based approach

 

[AA]

[Aa]

[aa]

G1

0

1ξ1

2ξ1

G2

0

1ξ2

0

  1. G1 and G2 are dummy variables representing a genetic bi-allelic variant. [AA], [Aa] and [aa] are genotypes, with ‘A’ being the reference allele. ξ1 and ξ2 are the effects associated with G1 and G2 respectively.
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BMC Medical Research Methodology

ISSN: 1471-2288

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