Table 7 Risk of seizure recurrence by treatment - sensitivity analyses (arm B)
From: Modelling seizure rates rather than time to an event within clinical trials of antiepileptic drugs
Variable | Hazard Ratio (95% CI) | |||
|---|---|---|---|---|
On randomised drug only | Recurrent tonic-clonic seizures only | On randomised drug only & recurrent tonic-clonic seizures only | ||
Treatment | Valproate | 1.00 | 1.00 | 1.00 |
Lamotrigine | 1.18 (1.01, 1.38) | 1.26 (1.06, 1.51) | 1.54 (1.23, 1.93) | |
Topiramate | 1.58 (1.33, 1.88) | 1.24 (1.03, 1.49) | 2.08 (1.64, 2.63) | |