Table 2 Descriptive summary of risk factors and biomarkers in ERP Study (N=70)
Category | Risk factor/Biomarker | Child age (week) | Mean ± SD or percentage |
|---|---|---|---|
Enteric inflammation | Myeloperoxidase (MPO) | 12 | 10057.57 ±9189.827 |
|  | Calprotectin | 12 | 933.41 ±679.94 |
|  | Neopterin | 12 | 2468.82 ±1644.28 |
|  | Alpha-1 anti-trypsin (ALA) | 12 | 0.88 ±0.62 |
|  | Mannitol in urine | 12 | 0.015 ±0.017 |
|  |  | 24 | 0.019 ±0.018 |
|  | Lithostathine-1-beta (Reg1B) | 6 | 59.50 ±84.59 |
|  |  | 12 | 59.89 ±72.70 |
|  | Days of diarrhea | 18 | 6.39 ±8.31 |
Systemic inflammation | Ferritin | 6 | 175.99 ±104.08 |
|  |  | 18 | 28.60 ±25.32 |
|  | C reactive protein (CRP) index | 6, 18, 40, 53, 104 | 2.51 ±1.19 |
|  | Soluble CD14 | 6 | 1736.29 ±568.87 |
|  |  | 18 | 2284.00 ±787.66 |
|  | Endocab lipopolysaccharide (LPS) | 6 | 37.11 ±5.57 |
|  |  | 18 | 29.75 ±71.70 |
|  | Log scale of activin | 6 | 6.49 ±1.13 |
| Â | Interleukin 1 beta (IL1b) | 18 | 37.1% (top 50%) |
| Â | Interleukin 4 (IL4) | 18 | 44.3% |
| Â | Interleukin 5 (IL5) | 18 | 38.6% (top 50%) |
| Â | Interleukin 6 (IL6) | 18 | 55.7% (top 50%) |
| Â | Interleukin 7 (IL7) | 18 | 75.7% (top 50%) |
| Â | Interleukin 10 (IL10) | 18 | 64.3% (top 50%) |
| Â | Macrophage inflammatory protein 1 Beta (MIP1b) | 18 | 38.6% (top 50%) |
| Â | Tumor necrosis factor alpha (TNFa) | 18 | 41.4% (top 50%) |
Nutritional | Vitamin D | 6 | 28.10 ±14.26 |
|  |  | 18 | 52.85 ±22.50 |
|  | Zinc | 6 | 690.30 ±105.64 |
|  |  | 18 | 768.41 ±136.78 |
|  | Retinol binding protein (RBP) | 6 | 28846.90 ±11315.83 |
|  |  | 18 | 36762.30 ±15422.36 |
|  | Height for age z score (HAZ) | Birth | -0.95 ±0.79 |
|  | Weight for age z score (WAZ) | Birth | -1.28 ±0.83 |
|  | Weight for height z score (WHZ) | Birth | -1.22 ±0.96 |
|  | Days of exclusive breast milk feeding | 18 | 102.81 ±40.06 |
Maternal health, SES | Monthly household expenditure | Enrollment | 12112.86 ±6761.06 |
|  | Monthly household income | Enrollment | 13505.71 ±8680.46 |
|  | Mother height (cm) | Enrollment | 149.82 ±5.74 |
|  | Mother weight (kg) | Enrollment | 49.33 ±10.91 |
Sanitation | Access to treated water | Enrollment | 58.6% |
| Â | Access to toilet with a septic tank | Enrollment | 67.1% |
| Â | Access to private toilet not shared with neighbors | Enrollment | 10.0% |
| Â | Covered drain near home | Enrollment | 65.7% |