Table 4 Log hazard ratios (sd) of the categorical variables in the marginal structural model with and without secular trend included as a predictor variable
Female | Male | |||
|---|---|---|---|---|
Secular trend not accounted | Secular trend accounted | Secular trend not accounted | Secular trend accounted | |
Statin initiation | −0.34 (0.03) | − 0.26 (0.03) | − 0.29 (0.03) | − 0.22 (0.03) |
Ethnicity: Asian other | − 0.05 (0.14) | 0.07 (0.14) | − 0.01 (0.12) | 0.10 (0.12) |
Bangladeshi | 0.24 (0.33) | 0.35 (0.33) | 0.71 (0.19) | 0.80 (0.19) |
Black | −0.11 (0.09) | −0.01 (0.09) | − 0.64 (0.10) | −0.56 (0.10) |
Chinese | −0.22 (0.27) | −0.13 (0.27) | − 0.86 (0.30) | −0.77 (0.30) |
Indian | 0.24 (0.09) | 0.31 (0.09) | 0.20 (0.07) | 0.26 (0.07) |
Other ethnic group | −0.39 (0.16) | −0.31 (0.16) | − 0.19 (0.12) | −0.11 (0.12) |
Pakistani | 0.21 (0.18) | 0.33 (0.18) | 0.66 (0.11) | 0.75 (0.11) |
Townsend = 2 | 0.10 (0.02) | 0.09 (0.02) | 0.01 (0.01) | 0.01 (0.01) |
Townsend = 3 | 0.12 (0.02) | 0.12 (0.02) | 0.08 (0.01) | 0.08 (0.01) |
Townsend = 4 | 0.18 (0.02) | 0.18 (0.02) | 0.14 (0.01) | 0.15 (0.01) |
Townsend = 5 (most deprived) | 0.31 (0.02) | 0.30 (0.02) | 0.24 (0.02) | 0.23 (0.02) |
Atrial fibrillation | 0.68 (0.03) | 0.68 (0.03) | 0.53 (0.03) | 0.53 (0.03) |
Atypical antipsychotic medication | 0.38 (0.07) | 0.52 (0.07) | 0.40 (0.09) | 0.55 (0.09) |
CKD stage 3/4/5 | 0.02 (0.05) | 0.14 (0.05) | 0.27 (0.05) | 0.33 (0.05) |
Corticosteroid use | 0.49 (0.04) | 0.49 (0.04) | 0.44 (0.04) | 0.42 (0.04) |
Type 1 diabetes | 0.84 (0.09) | 0.84 (0.09) | 0.41 (0.08) | 0.40 (0.08) |
Type 2 diabetes | 0.65 (0.02) | 0.63 (0.02) | 0.60 (0.02) | 0.58 (0.02) |
Erectile dysfunction | NA | NA | 0.16 (0.04) | 0.23 (0.04) |
Family history CHD | 0.15 (0.01) | 0.15 (0.01) | 0.25 (0.01) | 0.25 (0.01) |
HIV | 0.20 (0.71) | 0.27 (0.71) | 1.00 (0.19) | 1.08 (0.19) |
Hypertension | 0.18 (0.01) | 0.20 (0.01) | 0.20 (0.01) | 0.22 (0.01) |
Migraine | 0.17 (0.02) | 0.17 (0.02) | 0.19 (0.03) | 0.19 (0.03) |
Rheumatoid arthritis | 0.28 (0.03) | 0.28 (0.03) | 0.25 (0.05) | 0.25 (0.05) |
Severe mental illness | 0.36 (0.01) | 0.33 (0.01) | 0.28 (0.02) | 0.26 (0.02) |
Smoking = Ex | 0.11 (0.01) | 0.13 (0.01) | 0.09 (0.01) | 0.11 (0.01) |
Smoking = Current | 0.44 (0.01) | 0.44 (0.01) | 0.45 (0.01) | 0.46 (0.01) |
SLE | 0.40 (0.13) | 0.41 (0.13) | 0.26 (0.28) | 0.23 (0.28) |