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Table 2 Cause-Specific and Subdistribution Hazard Ratios Estimated from the Cause-Specific Hazard (CSHFPM) and Cause-Specific Subdistribution Hazard models (SDHFPM1, SDHFPM2 and Fine and Gray)

From: Methods of competing risks flexible parametric modeling for estimation of the risk of the first disease among HIV infected men

EventVariableSDHFPM1SDHFPM2Fine&Gray ModelCSHFPM
  SDHR (95% CI)SDHR (95% CI)SDHR (95% CI)CSHR (95% CI)
AIDSMACS recruitment    
1984–85 & 1987–90ReferenceReferenceReferenceReference
2001–3 & 2010.031(.004–.22).035(.005–.25).030(.004–.21).039(.005–.28)
*LR test<.0001<.0001 .001
Age at diagnosis    
<40ReferenceReferenceReferenceReference
≥40.69(.51–.93).69(.52–.93).70(.51–0.96).87(.64–1.18)
LR test.017.016 .38
Baseline CD4    
< 3501.83 (1.16–2.90)1.70(1.10–2.63)1.82(1.14–2.90)1.86(1.19–2.90)
350–5001.38(.99–1.93)1.32(.96–1.83)1.38(1.00–1.91)1.33(.96–1.84)
≥ 500ReferenceReferenceReferenceReference
LR test.016.038 .016
Non-AIDSMACS recruitment    
 1984–85 & 1987–90ReferenceReferenceReferenceReference
2001–3 & 20103.33(2.04–5.46)3.57(2.22–5.75)3.18(1.90–5.35)2.45(1.51–3.99)
LR test<.0001<.0001 .0009
Age at diagnosis    
<40ReferenceReferenceReferenceReference
≥402.88(1.93–4.31)3.57(2.21–5.77)2.51(1.72–3.68)3.72(2.34–5.90)
LR test<.0001<.0001 <.0001
Baseline CD4    
< 3501.13(.56–2.32).84(.43–1.66)1.11(.56–2.23)1.32(.65–2.68)
350–500.58(.30–1.13).58(.30–1.11).57(.29–1.12).68(.35–1.32)
≥ 500ReferenceReferenceReferenceReference
LR test.19.42 .33
DeathAge at diagnosis    
<40ReferenceReferenceReferenceReference
≥402.95(1.07–8.15)3.28(1.19–8.99)2.91(1.05–8.04)3.71(1.34–10.28)
LR test.037.021 .012
Baseline CD4    
< 350
350–5001.79(.57–5.63)1.91(.62–5.91)1.77(.57–5.54)2.04(.65–6.41)
≥ 500ReferenceReferenceReferenceReference
LR test.17.13 .18
  1. *LR test is the Likelihood Ratio test for evaluating the effect of each covariate in the multivariable SDHFPM1, SDHFPM2, and CSHFPM