Table 2 Cause-Specific and Subdistribution Hazard Ratios Estimated from the Cause-Specific Hazard (CSH_FPM) and Cause-Specific Subdistribution Hazard models (SDH_FPM1, SDH_FPM2 and Fine and Gray)

_SDHR (95% CI)

_SDHR (95% CI)

_SDHR (95% CI)

_CSHR (95% CI)

AIDS

MACS recruitment

1984–85 & 1987–90

Reference

Reference

Reference

Reference

2001–3 & 2010

.031(.004–.22)

.035(.005–.25)

.030(.004–.21)

.039(.005–.28)

*LR test

<.0001

<.0001

.001

Age at diagnosis

<40

Reference

Reference

Reference

Reference

≥40

.69(.51–.93)

.69(.52–.93)

.70(.51–0.96)

.87(.64–1.18)

LR test

.017

.016

.38

Baseline CD4

< 350

1.83 (1.16–2.90)

1.70(1.10–2.63)

1.82(1.14–2.90)

1.86(1.19–2.90)

350–500

1.38(.99–1.93)

1.32(.96–1.83)

1.38(1.00–1.91)

1.33(.96–1.84)

≥ 500

Reference

Reference

Reference

Reference

LR test

.016

.038

.016

Non-AIDS

MACS recruitment

1984–85 & 1987–90

Reference

Reference

Reference

Reference

2001–3 & 2010

3.33(2.04–5.46)

3.57(2.22–5.75)

3.18(1.90–5.35)

2.45(1.51–3.99)

LR test

<.0001

<.0001

.0009

Age at diagnosis

<40

Reference

Reference

Reference

Reference

≥40

2.88(1.93–4.31)

3.57(2.21–5.77)

2.51(1.72–3.68)

3.72(2.34–5.90)

LR test

<.0001

<.0001

<.0001

Baseline CD4

< 350

1.13(.56–2.32)

.84(.43–1.66)

1.11(.56–2.23)

1.32(.65–2.68)

350–500

.58(.30–1.13)

.58(.30–1.11)

.57(.29–1.12)

.68(.35–1.32)

≥ 500

Reference

Reference

Reference

Reference

LR test

.19

.42

.33

Death

Age at diagnosis

<40

Reference

Reference

Reference

Reference

≥40

2.95(1.07–8.15)

3.28(1.19–8.99)

2.91(1.05–8.04)

3.71(1.34–10.28)

LR test

.037

.021

.012

Baseline CD4

< 350

–

–

–

–

350–500

1.79(.57–5.63)

1.91(.62–5.91)

1.77(.57–5.54)

2.04(.65–6.41)

≥ 500

Reference

Reference

Reference

Reference

LR test

.17

.13

.18