Table 1 Overview of simulated scenarios
Networks | (interventions, direct comparisons) |
|---|---|
Network (a) | (A, B, C), 3 |
Network (b) | (A, B, C, D), 5 |
Network (c) | (A, B, C, D, E), 7 |
Network (d) | (A, B, C, D, E), 9 |
Network (e) | (A, B, C, D, E), 9, additional inconsistency for comparison D vs. E |
Inconsistency (\(\text {OR}_{BC}^{incon} = \text {OR}_{BC} \times \text {ROR}_{BC}\)) | |
No inconsistency | RORBC=1 |
Moderate inconsistency | RORBC=0.8 |
Severe inconsistency | RORBC=0.6 |
Heterogeneity | |
Very low heterogeneity | Ï„2=0.01 |
Low heterogeneity | Ï„2=0.1 |
Direct studies per pairwise comparison | k=5 |
Patients per study arm | n=100 |
True treatment effects | ORAB=…=ORDE=1.0 |
Baseline probability | pA=0.1 |
Replications | R=1000 |