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Table 3 TCA exposure classification and effect estimates with alternative control windows (n = 8828)

From: A data visualisation method for assessing exposure misclassification in case-crossover studies: the example of tricyclic antidepressants and the risk of hip fracture in older people

Control Window

TCA Exposure Classification

ORc (95% CI)

Continuous Usersa

Non-Usersa

Intermittent Usersb

Recent Stoppersb

1d

349

8244

127

108

1.18 (0.91–1.52)

2e

326

8247

150

105

1.43 (1.11–1.83)

  1. Adapted from [7]
  2. TCA Tricyclic antidepressant, OR Odds ratio, CI Confidence interval
  3. aExcluded from analysis due to concordant exposure between the case window and the control window
  4. bIncluded in analysis due to discordant exposure between the case window and the control window
  5. cOR for intermittent exposure compared with recent stopping
  6. dA control window of 101–150 days pre-fracture
  7. eA control window of 151–200 days pre-fracture