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Table 7 Unadjusted and corrected sensitivities and specificities of LFpen and FC in detection of NC

From: Comparative diagnostic accuracy studies with an imperfect reference standard – a comparison of correction methods

 

Methods

Accuracy measures

Unadjusted (95% CI)

Brenner (95% CI)

Staquet et al (95% CI)

Non-cavitated caries lesion (NC) – LFpen

 Sensitivity

0.69 (0.64, 0.73)

0.68 (0.63, 0.73)

0.70 (0.65, 0.75)

 Specificity

0.81 (0.65, 0.91)

0.44 (0.28, 0.61)

0.04 (0.01, 0.17)

Non-cavitated caries lesion (NC) – FC

 Sensitivity

0.44 (0.39, 0.50)

0.44 (0.39, 0.49)

0.45 (0.40, 0.50)

 Specificity

0.91 (0.76, 0.97)

0.65 (0.48, 0.79)

0.36 (0.22, 0.53)

  1. CI Confidence interval, LFpen Laser florescence pen, FC Fluorescence camera