Statistical analysis of two arm randomized pre-post designs with one post-treatment measurement

Table 3 Statistical analysis of the three simulated data examples

Scenario	Method	Estimate	Standard error	p-value
Homogeneous	*ANOVA*	−3.089	2.106	0.144
	*ANCOVA*I	−2.422	0.955	0.0121
	*ANOVA-Change*	−2.354	0.971	0.0163
	RM	−2.354	0.971	0.0163
	*cRM*	−2.434	0.944	0.0108
Heterogeneous (n₀ = 90, n₁ = 90)	*ANCOVA*I	−3.203	1.403^a	0.0235
			1.397^b	0.0231
			1.400^d	n/a
	*ANCOVA*II	−3.165	1.333^a	0.0187
			1.402^c	0.0252
			1.397^d	n/a
	*cRM*	−3.203	1.405	0.0241
Heterogeneous (n₀ = 60, n₁ = 120)	*ANCOVA*I	−3.416	1.415^a	0.0167
			1.279^b	0.0083
			1.281^d	n/a
	*ANCOVA*II	−3.399	1.376^a	0.0145
			1.258^c	0.0076
			1.260^d	n/a
	*cRM*	−3.396	1.262	0.0078

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