Evaluating the performance of propensity score matching based approaches in individual patient data meta-analysis

Table 5 Simulation results: variance of log(OR) by PSM-based approaches and data generation features

			Treatment Prevalence According to Study				50% Treatment Prevalence				30% Treatment Prevalence
OR	SD ^c	SD ^b	Across	Preferential	Random	Within	Across	Preferential	Random	Within	Across	Preferential	Random	Within
	(σ_1j)	(σ_0j)	Study	Study	Effect	Study	Study	Study	Effect	Study	Study	Study	Effect	Study
3	0.04	0.7	0.04	0.09	0.12	0.10	0.02	0.03	0.02	0.02	0.03	0.03	0.03	0.03
		1.4	0.07	0.12	0.17	0.15	0.03	0.03	0.04	0.03	0.04	0.04	0.05	0.05
		2.1	0.14	0.16	0.33	0.25	0.05	0.05	0.05	0.05	0.07	0.08	0.07	0.09
	0.08	0.7	0.05	0.07	0.13	0.11	0.02	0.03	0.02	0.02	0.03	0.03	0.03	0.03
		1.4	0.07	0.12	0.18	0.14	0.04	0.03	0.04	0.03	0.05	0.04	0.05	0.05
		2.1	0.14	0.17	0.34	0.25	0.05	0.05	0.05	0.05	0.06	0.08	0.06	0.08
1.5	0.04	0.7	0.04	0.07	0.12	0.12	0.02	0.03	0.03	0.02	0.03	0.03	0.03	0.03
		1.4	0.07	0.12	0.17	0.16	0.04	0.06	0.05	0.06	0.04	0.05	0.04	0.06
		2.1	0.12	0.20	0.33	0.32	0.05	0.06	0.05	0.06	0.07	0.08	0.07	0.09
	0.08	0.7	0.05	0.08	0.12	0.12	0.02	0.03	0.03	0.02	0.02	0.03	0.03	0.03
		1.4	0.06	0.13	0.16	0.16	0.05	0.06	0.05	0.06	0.04	0.05	0.04	0.06
		2.1	0.13	0.19	0.32	0.32	0.06	0.06	0.05	0.06	0.06	0.08	0.07	0.09

OR indicates pooled odds ratio used for simulation
^cSD is the standard deviation, σ_1j of study specific random slope, u_1j
^bSD is the standard deviation, σ_0j, of study specific random intercept, u_0j
Across-study indicates consideration of Single-level logit model with across-study matching
Prefer-study indicates consideration Single-level logit model with preferential-within study matching
Random-effect indicates consideration of Random-effect logit model with across-study matching
Within-study indicates consideration of Single-level logit model with within-study matching

ISSN: 1471-2288