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Fig. 19 | BMC Medical Research Methodology

Fig. 19

From: Analysis approaches to address treatment nonadherence in pragmatic trials with point-treatment settings: a simulation study

Fig. 19

95 percentage coverage probability versus treatment effect in risk difference for 10 percent and 40 percent nonadherence using DAG 2. The coverage probability for the ITT and baseline-adjusted ITT is less than 0.5 for some scenarios and out of the bound [0.5, 1]. Abbreviations: ITT: intention-to-treat, PP: per-protocol, AT: as-treated, IP-weighted PP: inverse probability-weighted per-protocol, 2SLS: two-stage least square, 2SRI: two-stage residual inclusion

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