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Fig. 3 | BMC Medical Research Methodology

Fig. 3

From: Analysis approaches to address treatment nonadherence in pragmatic trials with point-treatment settings: a simulation study

Fig. 3

Bias versus the nonadherence rate for the null and non-null effect for simulation setting 2. The naïve and both-stages adjusted 2SLS and 2SRI share the same line as they produce the same amount of bias. The baseline-adjusted PP and IP-weighted PP also share the same line. Abbreviations: RD: risk difference, PP: per-protocol, IP-weighted PP: inverse probability-weighted per-protocol, 2SLS: two-stage least square, 2SRI: two-stage residual inclusion

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BMC Medical Research Methodology

ISSN: 1471-2288

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