Table 3 Comparison of survival time and diagnosis date matching when comparing a rare real-world individual to 1 million synthetic individuals with matched covariate profiles
| Â | Real-World Individual Covariate Patterns | |||||
|---|---|---|---|---|---|---|
No of Observations | 1 | 3 | 3 | 2 | 1 | 1 |
Age at Diagnosis | 68 | 73 | 81 | 70 | 60 | 45 |
Sex | Female | Male | Female | Female | Male | Male |
Stage at Diagnosis | Localised | Localised | Distant | Regional | Distant | Localised |
Year of Diagnosis | 1994 | 1994 | 1992 | 1990 | 1993 | 1989 |
Anatomical Subsite | Other | Sigmoid | Coecum | Coecum | Transverse | Sigmoid |
Vital Status | Alive | Alive Alive Alive | Dead Dead Dead | Dead Alive | Dead | Alive |
Synthetic Vital Status (Alive/Dead%) | 94.74/5.25 | 89.36/10.64 | 9.92/90.08 | 44.07/55.93 | 17.22/82.78 | 78.44/21.56 |
Diagnosis Date | 15/9/1994 | 14/1/1994 15/10/1994 15/9/1994 | 21/12/1992 17/3/1992 15/4/1992 | 20/11/1990 16/5/1990 | 7/12/1993 | 14/11/1989 |
Synthetic Observations with Diagnosis Date ± 15 Days (%) | 8.65 | 7.75 8.32 8.57 | 7.01 8.36 8.68 | 8.56 8.37 | 8.42 | 8.56 |
Survival Time (Rounded to Nearest Day) | 472 | 716 442 472 | 16 46 868 | 351 2055 | 77 | 2238 |
Synthetic Observations with Survival Time ± 15 Days (%) | 8.43 | 6.74 4.10 8.10 | 11.61 15.77 0.45 | 1.61 3.77 | 7.26 | 7.01 |
Survival Time Matches per 1 Million Synthetic Patients | 2719 | 2282 2573 2633 | 4102 2187 156 | 2740 2670 | 1011 | 2225 |