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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: Comparing outcomes from tailored meta-analysis with outcomes from a setting specific test accuracy study using routine data of faecal calprotectin testing for inflammatory bowel disease

Fig. 1

ROC plot of studies reporting sensitivity and specificity of FC testing for IBD at 50 μg/g (binomial method). The applicable region for primary care is defined by the test positive rate (dashed line) and by test positive rate plus prevalence (trapezium) from THIN data defines the area of sensitivity and specificity that is compatible with UK primary care practices. Included studies using the binomial distribution method (Caviglia 2014 [9], Conroy 2018 [10] and DeSloovere 2017 [11]) were compatible with their true parameters lying in the applicable region unlike the rejected studies (Alrubaiy 2012 [12], Boyd 2016 [13], Carroccio 2003 [14], El Badry 2010 [15], Hogberg 2017 [16], Labaere 2014 [17], Li 2006 [18], Mowat 2016 [19], Oyaert 2017 [20], Oyaert 2014 [21] and Tan 2016 [22])

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BMC Medical Research Methodology

ISSN: 1471-2288

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