Table 1 Example for continuous endpoints. Mean responses for continuous endpoints according to the arm and the period in the presence of step-wise trends for scenarios presented in “Design” section and for λ0=λ2=0.1. Here X represents the mean response of arm 1 in period 2, which we vary in Fig. 3
From: On model-based time trend adjustments in platform trials with non-concurrent controls
Period 1 | Period 2 | |||||
|---|---|---|---|---|---|---|
Control | Arm 1 | Arm 2 | Control | Arm 1 | Arm 2 | |
H0 | 0 | 0.25 | – | 0.1 | X | 0.1 |
H1 | 0 | 0.25 | – | 0.1 | X | 0.35 |