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Table 5 Descriptive analysis for each variable used

From: Case-only approach applied in environmental epidemiology: 2 examples of interaction effect using the US National Health and Nutrition Examination Survey (NHANES) datasets

The preventive (negative) interaction effect between blood chromium levels and glycohemoglobin levels on albuminuria (micro and macro)

Environmental exposure

Normal chromium

Abnormal chromium

NA

 Number of subjects

1312

29

55

 Mean

0.35 μg/L

2.02 μg/L

NA

 Outcome (disease)

No albuminuria

Albuminuria

NA

 Number of subjects

1089

270

37

 Mean

9.49 mg/g

504.0 mg/g

NA

 Susceptibility factor

Blood glycohemoglobin level (with 48 NA values)

 Statistics

Min

Median

Mean

Max

 Value

4.1%

6.0%

6.39%

16.5%

The aggravating (positive) interaction effect between blood cobalt levels and old ages on albuminuria (micro and macro)

Environmental exposure

Normal cobalt

Abnormal cobalt

NA

 Number of subjects

6942

32

312

 Mean

0.18 μg/L

6.04 μg/L

NA

 Outcome (disease)

No albuminuria

Albuminuria

NA

 Number of subjects

5919

1179

188

 Mean

9.28 mg/g

335.0 mg/g

NA

 Susceptibility factor

Age in years (with no NA value)

 Statistics

Min

Median

Mean

Max

 Value

40.0 yrs

60.0 yrs

60.28 yrs

80.0 yrs

  1. NA not available (missing value), yrs years of age