Fig. 1
From: A dose-finding design for phase I clinical trials based on Bayesian stochastic approximation
Upper panel: one search path up to 10 steps for the target toxicity probability 0.2, where the observed values of \(y_n\) are depicted along the dose level by empty circles for 0 and filled bullets for 1. Lower panel: evolution of the posterior densities (multiplied by a certain constant for illustration purpose) of \(\theta\) after the sixth to tenth cohort. The dotted lines indicate the limits of the subintervals and the solid line indicates the root at 0.75