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Table 3 Estimates of conditional total, direct and indirect effects by extended imputation approach. \(M_{1}\): adverse reproductive outcomes. \(M_{2}\): infant lower respiratory infections

From: Applied causal inference methods for sequential mediators

 

Extended imputation approach

Conditional effect

PR

95% CI

Direct effect

1.57

1.28-1.86

Indirect effect through \(M_{1}\) and \(M_{2}\) jointly

1.05

1.00-1.09

Indirect effect through \(M_{1}\)

1.00

0.99-1.00

Partial indirect effect through \(M_{2}\)

1.05

1.00-1.09

Total effect

1.64

1.34-1.96

  1. PR: prevalence ratio; CI: confidence interval calculated by bootstrap