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Table 1 Description of 5433 participants in the English Longitudinal Study of Ageing at wave 2 (baseline 2004–2005) stratified by the apparition of events during the follow-up

From: Machine learning for predicting neurodegenerative diseases in the general older population: a cohort study

Characteristic

All sample (n = 5433)

No NDs events (n = 4742)

NDs events (n = 691)

Age, median (IQR), years

70 (12)

69 (10)

75 (13)

Sex, No. (%)

 Male No. (%)

2408 (44)

2123 (45)

285 (41)

 Married or cohabiting (%)a

3339 (61)

2948 (62)

391 (57)

 Education non-qualified a, b

2928 (54)

2511 (53)

417 (60)

 Former smoker (%)a

2773 (51)

2422 (51)

351 (51)

 Current smoker (%)a

691 (13)

606 (13)

85 (12)

 Sleep disturbance, No. (%)a

2274 (42)

1971 (42)

303 (44)

 BMI, mean (SD), kg/m2 a

28 (5)

28 (5)

28 (5)

 Obesity, No. (%) a, c

1546 (28)

1361 (29)

185 (27)

 Weight loss (%)

956 (18%)

809 (17)

147 (21)

Physical activity, No. (%)a

 Low level or inactive

1941 (36)

1626 (34)

315 (46)

 Moderate or vigorous

3492 (64)

3116 (66)

376 (54)

Gait speed, mean (SD), m/s a

0.84 (0.30)

0.85 (0.30)

0.74 (0.30)

Falls, No. (%)a

1789 (33)

1519 (32)

270 (39)

Systolic blood pressure, mean (SD), mmHga

138 (31)

138 (33)

139 (32)

Diastolic blood pressure, mean (SD), mmHga

74 (15)

74 (15)

73 (16)

Cardiovascular disease, No. (%)d

750 (14)

635 (13)

115 (17)

Stroke, No. (%)

344 (6)

289 (6)

55 (8)

Diabetes, No. (%) a, e

512 (9)

442 (9)

70 (10)

Hypertension, No. (%)e

2646 (49)

2294 (48)

352 (51)

Depression, No. (%)a, f

1765 (32)

1489 (31)

276 (40)

Cognition (executive), mean (SD), ppa

12 (3)

12 (3)

11 (3)

Cognition (memory), mean (SD), ppa

15 (4)

15 (4)

12 (4)

Psychiatric diagnosis, No. (%)e

425 (8)

369 (8)

56 (8)

  1. aImputed data and if SD, it was calculated according to Rubin’s rules
  2. bNo graduation certificate (primary or secondary studies)
  3. cDefined as BMI > = 30 kg/m2
  4. dDefined as self-reported infarction, stroke or heart failure
  5. eSelf-reported medical diagnosis
  6. fDefined as a score > =4 of the 8-item Center for Epidemiological Studies-Depression (CES-D). Abbreviations: NDs Neurodegenerative diseases, IQR Interquartile range, SD standard deviation, BMI Body mass index, pp. Per point