Table 1 Powers and required sample sizes in a real clinical trial
s.dist = “gamma” | s.dist = “indepExp” | |||||
|---|---|---|---|---|---|---|
rho (correlation of s with T1) | 0.1 | 0.3 | 0.5 | 0.7 | 0.9 | 0 |
Power at the significance level of 0.01 with n= 232 and r = 1 | 0.024 | 0.060 | 0.093 | 0.104 | 0.099 | 0.074 |
Required sample sizes (n) to attain the power of 0.9 at the significance level of 0.01 | > 10,000 | 3339 | 2276 | 2034 | 2084 | 2828 |