Table 7 Likelihood ratio test and normal approximation test results for analgesics. The columns are drug name, report count for male without the drug (No Drug/Male), report count for female without the drug (No Drug/Female), report count for male with the drug (Drug/Male), report count for female with the drug (Drug/Female), the likelihood ratio statistic with the adjusted p-value (in parentheses), and the z-score for the normal approximation test with the corresponding p-value. The Max-Stat method was used to adjust the p-values for multiple testing
Drug name | No Drug Male | No Drug Female | Drug Male | Drug Female | LRT(adj.p) | Normal Approx.(adj.p) |
|---|---|---|---|---|---|---|
Acetaminophen | 46798 | 51289 | 1032 | 1789 | 67.2388(0.0000) | 11.5059(0.0000) |
Aspirin | 47695 | 52984 | 135 | 94 | 6.1345(0.0062) | 3.5011(0.0055) |
Ibuprofen | 47566 | 52706 | 264 | 372 | 4.4538(0.0409) | 2.9749(0.0346) |
meloxicam | 47818 | 53044 | 12 | 34 | 4.3995(0.0433) | 2.8949(0.0446) |
Etodolac | 47821 | 53053 | 9 | 25 | 3.1308(0.1452) | 2.4440(0.1610) |
Indomethacin | 47820 | 53053 | 10 | 25 | 2.5873(0.2604) | 2.2308(0.2683) |
Ketoprofen | 47821 | 53073 | 9 | 5 | 0.8066(0.9482) | 1.2654(0.9370) |
Diclofenac | 47625 | 52822 | 205 | 256 | 0.7963(0.9504) | 1.2604(0.9387) |
Ketorolac | 47824 | 53067 | 6 | 11 | 0.5090(0.9867) | 0.9996(0.9898) |
Piroxicam | 47821 | 53063 | 9 | 15 | 0.4782(0.9925) | 0.9713(0.9920) |
nabumetone | 47825 | 53069 | 5 | 9 | 0.3902(0.9975) | 0.8756(0.9968) |
Naproxen | 47750 | 52982 | 80 | 96 | 0.1337(1.0000) | 0.5168(1.0000) |