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Table 6 The variance in estimation of the comparison of interest, \(\text {Var}(\hat{\mu }_{I,EQ})\), using the best connecting trial when the comparison of interest is I to EQ compared to the variance using a direct trial of I to EQ

From: Connecting a disconnected trial network with a new trial: optimizing the estimation of a comparative effect in a network meta-analysis

 

\(\text {Var}(\hat{\mu }_{I,EQ})\)

n

Best Connecting Trial

Direct Trial

6

DJ-E

3.0250

3.5180

8

H-E

2.3211

2.6385

10

H-E

1.8978

2.1108

12

H-E

1.6157

1.7590

14

H-E

1.4141

1.5077

16

I-E

1.2575

1.3193

18

I-E

1.1302

1.1727

20

I-E

1.0284

1.0554

50

I-EQ

0.4222

0.4222

100

I-EQ

0.2111

0.2111

200

I-EQ

0.1055

0.1055

500

I-EQ

0.0422

0.0422

1000

I-EQ

0.0211

0.0211