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Table 1 Values of parameters in the simulations

From: On the Q statistic with constant weights in meta-analysis of binary outcomes

Parameter

Equal study sizes

Unequal study sizes

K (number of studies)

5, 10, 30

n or \(\bar{n}\) (average (individual) study size —

20, 40, 100, 250

30 (12,16,18,20,84),

 total of the two arms)

 

60 (24,32,36,40,168),

 For \(K = 10\) and \(K = 30\), the same set of unequal

 

100 (64,72,76,80,208),

 study sizes is used twice or six times, respectively.

 

160 (124,132,136,140,268)

f (proportion of observations in the control arm)

1/2

\(p_{iC}\) (probability in the control arm)

.1, .2, .5

\(\theta\) (true value of LOR)

0, 0.1, 0.5, 1, 1.5, 2

\(\tau ^{2}\) (variance of random effects for LOR)

0(0.1)1

\(\rho\) (fixed value of LRR)

 

 For \(p_{iC} = .1\) or .2

\(-0.5\), 0, 0.5, 1, 1.5

 For \(p_{iC} = .5\)

\(-1.5\), \(-1\), \(-0.5\), 0, 0.5

\(p_T\) (fixed probability in the treatment arm)

 

 for RD (and for RR),

 

 when \(p_{iC} = .1\)

.06, .10, .16, .27, .45

 when \(p_{iC} = .2\)

.12, .20, .33, .54, .90

 when \(p_{iC} = .5\)

.11, .18, .30, .50, .82