Algorithm | TP | FP | TN | FN | Sensitivity | Specificity | NPV | PPV | Accuracy |
---|---|---|---|---|---|---|---|---|---|
1. ≥ 2 medical (inpatient and/or outpatient [both physicians’ office visits and all other outpatient settings]) encounters resulting in diagnoses OA of the hip and/or knee12 within 6 months | 350 | 7 | 40 | 93 | 0.79 | 0.85 | 0.30 | 0.98 | 0.80 |
2. ≥ 2 medical encounters resulting in diagnoses of OA of the hip and/or knee ≤ 90 days apart | 335 | 6 | 41 | 108 | 0.76 | 0.87 | 0.28 | 0.98 | 0.77 |
3. 1 inpatient admission resulting in a diagnosis of OA of the hip and/or knee | 239 | 2 | 45 | 204 | 0.54 | 0.96 | 0.18 | 0.99 | 0.58 |
4. A diagnosis of OA of the hip and/or knee from ≥ 1 outpatient visit | 401 | 21 | 26 | 42 | 0.91 | 0.55 | 0.38 | 0.95 | 0.87 |
5. A diagnosis of OA of the hip and/or knee from ≥ 2 outpatient visits in the same CY | 345 | 6 | 41 | 98 | 0.78 | 0.87 | 0.29 | 0.98 | 0.79 |
6. A diagnosis of OA of the hip and/or knee from ≥ 3 outpatient visits in the same CY | 294 | 6 | 41 | 149 | 0.66 | 0.87 | 0.22 | 0.98 | 0.68 |
7. A diagnosis of OA of the hip and/or knee from ≥ 4 outpatient visits in the same CY | 263 | 2 | 45 | 180 | 0.59 | 0.96 | 0.20 | 0.99 | 0.63 |
8. A diagnosis of OA of the hip and/or knee from ≥ 1 outpatient visit; and ≥ X-rays of the hip and/or knee in the same CY | 351 | 10 | 37 | 92 | 0.79 | 0.79 | 0.29 | 0.97 | 0.79 |
9. A diagnosis of OA of the hip and/or knee from ≥ 2 outpatient visits; and ≥ X-rays of the hip and/or knee in the same CY | 318 | 3 | 44 | 125 | 0.72 | 0.94 | 0.26 | 0.99 | 0.74 |
10. A diagnosis of OA of the hip and/or knee from ≥ 3 outpatient visits; and ≥ X-rays of the hip and/or knee in the same CY | 270 | 3 | 44 | 173 | 0.61 | 0.94 | 0.20 | 0.99 | 0.64 |
11. A diagnosis of OA of the hip and/or knee from ≥ 4 outpatient visits; and ≥ X-rays of the hip and/or knee in the same CY | 244 | 1 | 46 | 199 | 0.55 | 0.98 | 0.19 | 1.00 | 0.59 |
12. 1 outpatient visit and ≥ 2 diagnoses of OA of the hip and/or knee from outpatient visits within 5 years | 274 | 5 | 42 | 169 | 0.62 | 0.89 | 0.20 | 0.98 | 0.64 |
13. ≥ 2 outpatient visits resulting in diagnoses of OA of the hip and/or knee within 5 years | 351 | 6 | 41 | 92 | 0.79 | 0.87 | 0.31 | 0.98 | 0.80 |
14. ≥ 2 outpatient visits resulting in diagnoses of OA of the hip and/or knee within 2 years | 351 | 6 | 41 | 92 | 0.79 | 0.87 | 0.31 | 0.98 | 0.80 |
15. ≥ 1 medical encounter resulting in a diagnosis of OA of the hip and/or knee | 401 | 21 | 26 | 42 | 0.91 | 0.55 | 0.38 | 0.95 | 0.87 |
16. ≥ 1 medical encounter resulting in a diagnosis of OA of the hip or knee plus ≥ 1 medical encounter resulting in a diagnosis of joint pain ≥ 30 days apart | 325 | 4 | 43 | 118 | 0.73 | 0.91 | 0.27 | 0.99 | 0.75 |
17. ≥ 1 medical encounter resulting in a diagnosis of OA of the hip or knee plus ≥ 1 administration of either HA or IA corticosteroids | 316 | 8 | 39 | 127 | 0.71 | 0.83 | 0.23 | 0.98 | 0.72 |
18. ≥ 1 medical encounter resulting in a diagnosis of OA of the hip or knee plus ≥ 1 relevant scans (i.e., X-ray, MRI) of knee or hip ± 2 years of the OA diagnosis | 358 | 7 | 40 | 85 | 0.81 | 0.85 | 0.32 | 0.98 | 0.81 |
19. ≥ 1 medical encounter resulting in a diagnosis of OA of the hip or knee plus ≥ 1 procedure codes for knee or hip arthroplasty (partial or full; initial or revision) within 30 days after OA diagnosis | 231 | 0 | 47 | 212 | 0.52 | 1.00 | 0.18 | 1.00 | 0.57 |
20. ≥ 1 medical encounter resulting in a diagnosis of OA of the hip or knee plus ≥ 1 mobility aid (e.g., cane, walker, wheelchair) ± 30 days of OA diagnosis | 79 | 2 | 45 | 364 | 0.18 | 0.96 | 0.11 | 0.98 | 0.25 |
Combined Algorithm (using OR function) | |||||||||
Combinations of all algorithms with performance ≥ 0.98 PPV | 382 | 11 | 36 | 61 | 0.86 | 0.77 | 0.37 | 0.97 | 0.85 |
Combinations of all algorithms with performance ≥ 0.95 PPV | 403 | 21 | 26 | 40 | 0.91 | 0.55 | 0.39 | 0.95 | 0.88 |
Combinations of all algorithms with performance ≥ 0.90 PPV | 403 | 21 | 26 | 40 | 0.91 | 0.55 | 0.39 | 0.95 | 0.88 |
Combinations of all algorithms with performance ≥ 0.85 PPV | 403 | 21 | 26 | 40 | 0.91 | 0.55 | 0.39 | 0.95 | 0.88 |
Combinations of all algorithms with performance ≥ 0.80 PPV | 403 | 21 | 26 | 40 | 0.91 | 0.55 | 0.39 | 0.95 | 0.88 |