Algorithm | TP | FP | TN | FN | Sensitivity | Specificity | NPV | PPV | Accuracy |
---|---|---|---|---|---|---|---|---|---|
1. Receipt of HA, IA corticosteroid, and/or nerve block preceded by receipt of 2 different classes of analgesics (i.e., NSAIDs [including COX-2 inhibitors], opioids) | 10 | 0 | 127 | 353 | 0.03 | 1.00 | 0.26 | 1.00 | 0.28 |
2. Receipt of ≥ 3 analgesic classes | 44 | 1 | 126 | 319 | 0.12 | 0.99 | 0.28 | 0.98 | 0.35 |
3. Receipt of knee or hip arthroplasty (partial or complete; original or revision) | 258 | 6 | 121 | 105 | 0.71 | 0.95 | 0.54 | 0.98 | 0.77 |
4. Receipt of nerve block | 210 | 19 | 108 | 153 | 0.58 | 0.85 | 0.41 | 0.92 | 0.65 |
5. Receipt of ≥ 2 different opioids within a 90-day period | 24 | 4 | 123 | 339 | 0.07 | 0.97 | 0.27 | 0.86 | 0.30 |
6. Receipt of a mobility aid (as described above) within 90-day period subsequent to receipt of an opioid | 12 | 0 | 127 | 351 | 0.03 | 1.00 | 0.27 | 1.00 | 0.28 |
Combined algorithm (using OR function) | |||||||||
Combinations of all algorithms with performance ≥ 0.98 PPV | 21 | 0 | 127 | 342 | 0.06 | 1.00 | 0.27 | 1.00 | 0.30 |
Combinations of all algorithms with performance ≥ 0.95 PPV | 262 | 6 | 121 | 101 | 0.72 | 0.95 | 0.55 | 0.98 | 0.78 |
Combinations of all algorithms with performance ≥ 0.90 PPV | 290 | 23 | 104 | 73 | 0.80 | 0.82 | 0.59 | 0.93 | 0.80 |
Combinations of all algorithms with performance ≥ 0.85 PPV | 291 | 25 | 102 | 72 | 0.80 | 0.80 | 0.59 | 0.92 | 0.80 |
Combinations of all algorithms with performance ≥ 0.80 PPV | 291 | 25 | 102 | 72 | 0.80 | 0.80 | 0.59 | 0.92 | 0.80 |