Original analysis on rate ratio scale | |||||
Group | No. subjects | PYFU | Incident HIV infections | Incidence rate (per 100 PYFU) | Rate ratio (95% CI) |
TDF/FTC | 2693 | 4386 | 11 | 0.251 | REF |
TAF/FTC | 2694 | 4370 | 6 | 0.137 | 0.55 (0.20, 1.48) |
Re-analysis using an averted infections framework | |||||
Group | PYFU | Observed infections | Predicted infectionsa | Averted infections | Averted infections ratio (95% CI) |
TDF/FTC | 4386 | 11 | 90.4 | 79.4 | REF |
TAF/FTC | 4370 | 6 | 90.0 | 84.0 | 1.06 (0.96–1.17) |