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Fig. 2 | BMC Medical Research Methodology

Fig. 2

From: Sequential regression and simulation: a method for estimating causal effects from heterogeneous clinical trials without a common control group

Fig. 2

Summary of randomized controlled trial study designs. Data harmonization required careful understanding of the study designs. All treatment arms that involved 8 weeks of consistent exposure to either placebo or (blue) or active treatment at the FDA-approved doses (red) were included. R = randomized and blinded; O = open label

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BMC Medical Research Methodology

ISSN: 1471-2288

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