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Table 2 Summary of the clinical trial demographic characteristics

From: A systematic review of randomised controlled trials with adaptive and traditional group sequential designs – applications in cardiovascular clinical trials

 

Traditional group sequential design (n = 43)

Adaptive design

(n = 13)

No.

Percentages

No.

Percentages

Funders

    

 Public

9

20.9%

2

15.4%

 Commercial (company)

33

76.7%

11

84.6%

 None

1

2.3%

0

0

Country

(chief investigator)

    

 USA

18

41.9%

10

76.9%

 European

13

30.2%

3

23.1%

 Others*

12

27.9%

0

0

Centres/sites

    

 1

2

4.7%

1

7.7%

 2–49

5

11.6%

3

23.1%

 50–99

8

18.6%

4

30.8%

 100–199

6

14%

2

15.4%

 200–299

4

9.3%

2

15.4%

 300–499

4

9.3%

0

0

 500–799

7

16.3%

1

7.7%

 800-1,100

7

16.3%

0

0

  1. * Japan, Canada, Norway, Singapore, Thailand, Denmark, Sweden and Australia