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Fig. 2 | BMC Medical Research Methodology

Fig. 2

From: Functional data analysis to characterize disease patterns in frequent longitudinal data: application to bacterial vaginal microbiota patterns using weekly Nugent scores and identification of pattern-specific risk factors

Fig. 2

Clustering results of Ferraty & Vieu’s FDA method. This figure shows clusters obtained by Ferraty & Vieu’s FDA clustering method described in the “Functional data clustering algorithm using FPC [4]” section. Only the feature of small ball proportions was used for clustering, resulting in 2 clusters. Cluster 1 (top panel) suggests more fluctuations of Nugent scores over time, and Cluster 2 suggests more stable Nugent scores. However, Cluster 2 (bottom panel) does not differentiate women with stable high Nugent scores (i.e. with BV) versus women with low Nugent scores (i.e. no BV) which clearly are two distinct biological states

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