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Table 2 Risk factors associated with Class B (fluctuating) compared to Class A (normal) using Multinomial Logistic GEE Regression

From: Functional data analysis to characterize disease patterns in frequent longitudinal data: application to bacterial vaginal microbiota patterns using weekly Nugent scores and identification of pattern-specific risk factors

Covariates

Comparisons

Odds Ratio

95% CI

p-value

Nugent score at start of interval (\(BV_{0}\))

Every unit increase in Nugent score

1.26

[1.17,1.34]

<0.0001

Indicator Variables

    

HIV/AIDS status

HIV+ with no symptoms vs. HIV-

1.56

[0.52,4.67]

0.43

HIV+ with symptoms vs. HIV-

0.32

[0.08,1.39]

0.13

Age at baseline

\((\ge 20, <25)\) vs. \(<20\)

0.37

[0.18,0.76]

0.007

\((\ge 25, < 30)\) vs. \(<20\)

0.43

[0.21,0.90]

0.025

\(\ge 30\) vs. \(<20\)

0.59

[0.28,1.24]

0.16

Genital ulcer in past six months

yes vs. no

1.08

[0.31,3.79]

0.90

Pregnancy test

pregnant vs. not pregnant

0.58

[0.27,1.26]

0.17

Source of bathing water

partially protected vs. protected

0.74

[0.39,1.41]

0.36

unprotected vs. protected

0.841

[0.43, 1.64]

0.61

Current family planning use

birth control pills vs. none

1.16

[0.49,2.78]

0.74

Injectable/Norplant vs. none

1.20

[0.68,2.13]

0.53

Sexual frequency

< median vs. no sex

1.25

[0.53,2.94]

0.61

> median vs. no sex

1.376

[0.56,3.39]

0.49

Condom use

inconsistent vs. always use or no sex

1.51

[0.84, 2.71]

0.17

never used vs. always use or no sex

0.99

[0.37, 2.66]

0.99

Partner’s circumcision status

circumcised vs. not

0.79

[0.48,1.29]

0.34