Fig. 1From: Study methodology and insights from the palovarotene clinical development program in fibrodysplasia ossificans progressivaAn overview of the palovarotene clinical development program for FOP. Across the clinical development program, 164 individuals with FOP had received at least one dose of palovarotene. aIncludes 5 new individuals who had not participated in any previous study. bIn PVO-1A-202 Part D annual assessments were obtained following the last dose of palovarotene in participants who were skeletally immature at the time of treatment discontinuation. FOP: fibrodysplasia ossificans progressiva; NHS: natural history study; OLE: open-label extension; PVO: palovarotene; RCT: randomized controlled trialBack to article page