Skip to main content
Fig. 5 | BMC Medical Research Methodology

Fig. 5

From: How important is the linearity assumption in a sample size calculation for a randomised controlled trial where treatment is anticipated to affect a rate of change?

Fig. 5

Top panels: mean sample sizes and inter-quartile range, for a 5-year (left) and 3-year trial (right) calculated using the observational studies, for the larger residual error variance. Bottom panel: sample sizes determined using mean covariance parameters estimated in the 5000 observational studies (or the true data generation parameters for steady decline trajectory) for a range of trial lengths

Back to article page

BMC Medical Research Methodology

ISSN: 1471-2288

Contact us