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Table 2 Characteristics of Validation Cohort

From: Implementation and external validation of the Cambridge Multimorbidity Score in the UK Biobank cohort

 

Whole cohort

No conditions

1 condition

 > 1 condition

Counts

n (%)

111,898 (100)

57,319 (51.2)

28,841 (25.8)

25,738 (23.0)

Cohort Characteristics

Age

Mean (SD)

57.0 (8.0)

55.0 (8.0)

58.0 (7.6)

60.0 (7.0)

Missing (%)

0 (0)

0 (0)

0 (0)

0 (0)

 Sex

Female (%)

60,036 (53.7)

30,165 (52.6)

15,557 (53.9)

14,314 (55.6)

Male (%)

51,862 (46.3)

27,154 (47.4)

13,284 (46.1)

11,424 (44.4)

Missing (%)

0 (0)

0 (0)

0 (0)

0 (0)

 Smoking Status

Never (%)

61,638 (55.1)

33,956 (59.2)

15,402 (53.4)

12,280 (47.7)

Former (%)

38,845 (34.7)

17,669 (30.8)

10,615 (36.8)

10,561 (41.0)

Current (%)

10,864 (9.7)

5475 (9.5)

2678 (9.3)

2711 (10.5)

Missing (%)

551 (0.49)

219 (0.38)

146 (0.51)

186 (0.72)

 Deprivation Quintiles (English IMD)

1 (least deprived)

29,789 (26.6)

16,323 (28.5)

7644 (26.5)

5822 (22.6)

2

26,247 (23.5)

13,893 (24.2)

6724 (23.3)

5630 (21.9)

3

22,008 (19.7)

11,224 (19.6)

5718 (19.8)

5066 (19.7)

4

18,082 (16.2)

8735 (15.2)

4780 (16.6)

4567 (17.7)

5 (most deprived)

12,460 (11.1)

5447 (9.5)

3141 (10.9)

3872 (15.0)

Missing (%)

3312 (3.0)

1697 (3.0)

834 (2.9)

781 (3.0)

 BMI

Mean (sd)

27.4 (4.7)

26.6 (4.2)

27.7 (4.7)

29.0 (5.3)

 < 20 (%)

2444 (2.2)

1470 (2.6)

577 (2.0)

397 (1.5)

20—24.9 (%)

33,265 (29.7)

20,266 (35.4)

7780 (27.0)

5219 (20.3)

25—29.9 (%)

46,958 (42.0)

24,310 (42.4)

12,490 (43.3)

10,158 (39.5)

 ≥ 30 (%)

26,349 (23.5)

9924 (17.3)

7271 (25.2)

9154 (35.6)

Missing (%)

2882 (2.6)

1349 (2.4)

723 (2.5)

810 (3.1)

Outcome measures

 Deaths

Number in 1 year (%)

161 (0.14)

42 (0.07)

29 (0.10)

90 (0.35)

Number in 5 years (%)

1987 (1.77)

587 (1.02)

522 (1.81)

878 (3.41)

 Cancer Diagnoses

Number in 1 year (%)

1071 (0.96)

432 (0.75)

307 (1.06)

332 (1.29)

Number in 5 years (%)

5589 (5.0)

2377 (4.15)

1565 (5.43)

1647 (6.40)

 GP Consultation Rate

Rate per year, Median (IQR)

7.68 (4.78–11.73)

5.54 (3.53–8.34)

8.77 (6.19–12.2)

12.46 (8.95–17.6)

Zero consultations (%)

43 (0.04)

28 (0.05)

7 (0.02)

8 (0.03)

 GP Follow-up (years)

Median (IQR)

7.03 (6.48–7.61)

7.05 (6.56–7.62)

7.02 (6.48–7.59)

7.00 (6.41–7.57)