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Table 2 Comparison of MELD coefficients for different model fits “from registration” (panel A) and “from cross-section” (panel B), for (1) revision with ReMELD’s prognostic index as an offset, (2) revision without the offset, and (3) revision with IPCW

From: Revising model for end-stage liver disease from calendar-time cross-sections with correction for selection bias

Panel A—"From registration"

 

Time to death from baseline, 90d

 

(1) ReMELD offset

(2) Refitted, no IPCW

(3) Refitted, IPCW

 log(creatininea (mg/dL))

0.10 (0.09)

1.62 (0.01)

1.61 (0.12)

 log(bilirubin (mg/dL))

0.03 (0.05)

0.69 (0.05)

0.73 (0.06)

 log(INR)

0.12 (0.17)

2.02 (0.17)

2.19 (0.21)

 Biweekly dialysis

 

1.85 (0.12)

1.73 (0.13)

 LR Test

4.1 (df = 3)

1482 (df = 4)

1883 (df = 4)

Panel B—"From cross-section"

 

Time to waitlist death from cross-section, 90d

 

(1) ReMELD offset

(2) Refitted, no IPCW

(3) Refitted, IPCW

 log(creatininea (mg/dl))

0.40 (0.08)

2.07 (0.08)

2.15 (0.08)

 log(bilirubin (mg/dl))

0.22 (0.04)

0.92 (0.04)

0.97 (0.04)

 log(INR)

0.04 (0.13)

2.06 (0.13)

2.22 (0.15)

 Biweekly dialysis

 

1.87 (0.12)

1.86 (0.12)

 LR Test

801 (df = 3)

22 197 (df = 4)

26 933 (df = 4)

  1. acreatinine set to 1.0 if on dialysis