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Fig. 1 | BMC Medical Research Methodology

Fig. 1

From: Distributive randomization: a pragmatic fractional factorial design to screen or evaluate multiple simultaneous interventions in a clinical trial

Fig. 1

Distributive trials versus other possible designs for parallel evaluation. The situation shown is that of 4 candidate interventions, numbered 1 to 4 and color-coded, with 2 maximum interventions in each patient due to toxicity or participant burden. Each white rectangle represents a possible combination of allocations in one patient (all possibilities are shown), and each gray rectangle represents a trial

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BMC Medical Research Methodology

ISSN: 1471-2288

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