Table 5 Result of cut point selection with different methods by MDA and their diagnostic properties
Methods | Cut-point (μmol/L) | Se (95%CI) | Sp (95%CI) | PPV (95%CI) | NPV (95%CI) | LR +  (95%CI) | LR- (95%CI) | DOR (95%CI) |
|---|---|---|---|---|---|---|---|---|
Youden | 2.1 | 0.50 (0.31,0.68) | 0.93 (0.77,0.99) | 0.88 (0.63,0.98) | 0.65 (0.49,0.78) | 7.50 (1.43,35.49) | 0.54 (0.10,2.67) | 14 (2.81,69.56) |
Euclidian | 1.7 | 0.73 (0.54,0.87) | 0.67 (0.47,0.82) | 0.69 (0.49,0.83) | 0.71 (0.51,0.86) | 2.20 (0.72,6.70) | 0.40 (0.13,1.22) | 5.50 (1.81,16.68) |
Product | 1.7 | 0.73 (0.54,0.87) | 0.67 (0.47,0.82) | 0.69 (0.49,0.83) | 0.71 (0.51,0.86) | 2.20 (0.72,6.70) | 0.40 (0.13,1.22) | 5.50 (1.81,16.68) |
DOR | 2.3 | 0.43 (0.25,0.62) | 0.97 (0.82,0.99) | 0.93 (0.66,0.99) | 0.63 (0.47,0.76) | 13 (1.71,119.44) | 0.58 (0.07,4.89) | 22.18 (2.66,184.80) |
IU | 1.7 | 0.73 (0.54,0.87) | 0.67 (0.47,0.82) | 0.69 (0.49,0.83) | 0.71 (0.51,0.86) | 2.20 (0.72,6.70) | 0.40 (0.13,1.22) | 5.50 (1.81,16.68) |