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  1. The most commonly used survey methods are self-administered questionnaires, telephone interviews, and a mixture of both. But until now evidence out of randomised controlled trials as to whether patient respons...

    Authors: Margitta Lungenhausen, Stefan Lange, Christoph Maier, Claudia Schaub, Hans J Trampisch and Heinz G Endres
    Citation: BMC Medical Research Methodology 2007 7:50
  2. Although there have been reported benefits of health education interventions across various health issues, the key to program effectiveness is participation and retention. Unfortunately, not everyone is willin...

    Authors: Enza Gucciardi, Jill I Cameron, Chen Di Liao, Alison Palmer and Donna E Stewart
    Citation: BMC Medical Research Methodology 2007 7:47
  3. The lack of robust systems for monitoring quality in healthcare has been highlighted. Statistical process control (SPC) methods, utilizing the increasingly available routinely collected electronic patient reco...

    Authors: Thabani Sibanda and Nokuthaba Sibanda
    Citation: BMC Medical Research Methodology 2007 7:46
  4. Birth weight and length have seasonal fluctuations. Previous analyses of birth weight by latitude effects identified seemingly contradictory results, showing both 6 and 12 monthly periodicities in weight. The ...

    Authors: John McGrath, Adrian Barnett, Darryl Eyles, Thomas Burne, Carsten B Pedersen and Preben Bo Mortensen
    Citation: BMC Medical Research Methodology 2007 7:45
  5. In an effort to identify previously unrecognized aspects of editorial decision-making, we explored the words and phrases that one group of editors used during their meetings.

    Authors: Kay Dickersin, Elizabeth Ssemanda, Catherine Mansell and Drummond Rennie
    Citation: BMC Medical Research Methodology 2007 7:44
  6. Disorders related to pregnancy and childbirth are a major health issue in South East Asia. They represent one of the biggest health risk differentials between the developed and developing world. Our broad rese...

    Authors: David J Henderson-Smart, Pisake Lumbiganon, Mario R Festin, Jacqueline J Ho, Hakimi Mohammad, Steve J McDonald, Sally Green and Caroline A Crowther
    Citation: BMC Medical Research Methodology 2007 7:43
  7. Recruiting and retaining GPs for research can prove difficult, and may result in sub-optimal patient participation where GPs are required to recruit patients. Low participation rates may affect the validity of...

    Authors: Michelle K Williamson, Jane Pirkis, Jon J Pfaff, Orla Tyson, Moira Sim, Ngaire Kerse, Nicola T Lautenschlager, Nigel P Stocks and Osvaldo P Almeida
    Citation: BMC Medical Research Methodology 2007 7:42
  8. We aimed at assessing the degree of measurement error in essential fatty acid intakes from a food frequency questionnaire and the impact of correcting for such an error on precision and bias of odds ratios in ...

    Authors: May A Beydoun, Jay S Kaufman, Joseph Ibrahim, Jessie A Satia and Gerardo Heiss
    Citation: BMC Medical Research Methodology 2007 7:41
  9. This study compares the Bayesian and frequentist (non-Bayesian) approaches in the modelling of the association between the risk of preterm birth and maternal proximity to hazardous waste and pollution from the...

    Authors: Afisi S Ismaila, Angelo Canty and Lehana Thabane
    Citation: BMC Medical Research Methodology 2007 7:39
  10. The Bayesian approach is now widely recognised as a proper framework for analysing risk in health care. However, the traditional text-book Bayesian approach is in many cases difficult to implement, as it is ba...

    Authors: Terje Aven and Karianne Eidesen
    Citation: BMC Medical Research Methodology 2007 7:38
  11. The widespread international use of the 26-item WHO Quality of Life Instrument (WHOQOL-Bref) necessitates the assessment of its factor structure across cultures. For, alternative factor models may provide a be...

    Authors: Jude U Ohaeri, Abdel W Awadalla, Abdul-Hamid M El-Abassi and Anila Jacob
    Citation: BMC Medical Research Methodology 2007 7:37
  12. The purpose of this study was to validate the accuracy of an alternative cervical cancer test – visual inspection with acetic acid (VIA) – by addressing possible imperfections in the gold standard through late...

    Authors: Lynne Gaffikin, John A McGrath, Marc Arbyn and Paul D Blumenthal
    Citation: BMC Medical Research Methodology 2007 7:36
  13. Missing data is a challenging problem in many prognostic studies. Multiple imputation (MI) accounts for imputation uncertainty that allows for adequate statistical testing. We developed and tested a methodolog...

    Authors: Martijn W Heymans, Stef van Buuren, Dirk L Knol, Willem van Mechelen and Henrica CW de Vet
    Citation: BMC Medical Research Methodology 2007 7:33
  14. With the advent of high throughput genotyping technology and the information available via projects such as the human genome sequencing and the HapMap project, more and more data relevant to the study of genet...

    Authors: Angela J Frodsham and Julian PT Higgins
    Citation: BMC Medical Research Methodology 2007 7:31
  15. The 'Hawthorne Effect' may be an important factor affecting the generalisability of clinical research to routine practice, but has been little studied. Hawthorne Effects have been reported in previous clinical...

    Authors: Rob McCarney, James Warner, Steve Iliffe, Robbert van Haselen, Mark Griffin and Peter Fisher
    Citation: BMC Medical Research Methodology 2007 7:30
  16. Hierarchical modelling represents a statistical method used to analyze nested data, as those concerning patients afferent to different hospitals. Aim of this paper is to build a hierarchical regression model u...

    Authors: Paola D'Errigo, Maria E Tosti, Danilo Fusco, Carlo A Perucci and Fulvia Seccareccia
    Citation: BMC Medical Research Methodology 2007 7:29
  17. Information overload, increasing time constraints, and inappropriate search strategies complicate the detection of clinical practice guidelines (CPGs). The aim of this study was to provide clinicians with reco...

    Authors: Andrea Haase, Markus Follmann, Guido Skipka and Hanna Kirchner
    Citation: BMC Medical Research Methodology 2007 7:28
  18. Data for health surveys are often collected using either mailed questionnaires, telephone interviews or a combination. Mode of data collection can affect the propensity to refuse to respond and result in diffe...

    Authors: Helene Feveile, Ole Olsen and Annie Hogh
    Citation: BMC Medical Research Methodology 2007 7:27
  19. Understanding the relationships between physical activity (PA) and disease has become a major area of research interest. Activity monitors, devices that quantify free-living PA for prolonged periods of time (d...

    Authors: David R Paul, Matthew Kramer, Alanna J Moshfegh, David J Baer and William V Rumpler
    Citation: BMC Medical Research Methodology 2007 7:26
  20. There is much evidence to suggest that risk for common clinical disorders begins in foetal life. Exposure to environmental risk factors however is often not random. Many commonly used indices of prenatal adver...

    Authors: Anita Thapar, Gordon Harold, Frances Rice, XiaoJia Ge, Jacky Boivin, Dale Hay, Marianne van den Bree and Allyson Lewis
    Citation: BMC Medical Research Methodology 2007 7:25
  21. To investigate the interchangeability of measures of disability and health-related quality of life (HRQL) by comparing their associations patterns with disease-related impairment measures in patients with a va...

    Authors: Nadine Weisscher, Rob J de Haan and Marinus Vermeulen
    Citation: BMC Medical Research Methodology 2007 7:24
  22. The choice between paper data collection methods and electronic data collection (EDC) methods has become a key question for clinical researchers. There remains a need to examine potential benefits, efficiencie...

    Authors: Soe Soe Thwin, Kerri M Clough-Gorr, Maribet C McCarty, Timothy L Lash, Sharon H Alford, Diana SM Buist, Shelley M Enger, Terry S Field, Floyd Frost, Feifei Wei and Rebecca A Silliman
    Citation: BMC Medical Research Methodology 2007 7:23
  23. The ability to locate those sampled has important implications for response rates and thus the success of survey research. The purpose of this study was to examine predictors of locating women requiring tracin...

    Authors: Suzanne M Cadarette, Leigh Dickson, Monique AM Gignac, Dorcas E Beaton, Susan B Jaglal and Gillian A Hawker
    Citation: BMC Medical Research Methodology 2007 7:22
  24. Claims data provide rapid indicators of SSIs for coronary artery bypass surgery and have been shown to successfully rank hospitals by SSI rates. We now operationalize this method for use by payers without tran...

    Authors: Susan S Huang, James M Livingston, Nigel SB Rawson, Steven Schmaltz and Richard Platt
    Citation: BMC Medical Research Methodology 2007 7:20
  25. Questionnaires are used routinely in clinical research to measure health status and quality of life. Questionnaire measurements are traditionally formally assessed by indices of reliability (the degree of meas...

    Authors: Matthew Hankins
    Citation: BMC Medical Research Methodology 2007 7:19
  26. Analyzing drop out rates and when they occur may give important information about the patient characteristics and trial characteristics that affect the overall uptake of an intervention.

    Authors: Carl Heneghan, Rafael Perera, Alison Ward A, David Fitzmaurice, Emma Meats and Paul Glasziou
    Citation: BMC Medical Research Methodology 2007 7:18
  27. Pragmatic randomised controlled trials are often used in primary care to evaluate the effect of a treatment strategy. In these trials it is difficult to achieve both high internal validity and high generalisab...

    Authors: Gerdine AJ Fransen, Corine J van Marrewijk, Suhreta Mujakovic, Jean WM Muris, Robert JF Laheij, Mattijs E Numans, Niek J de Wit, Melvin Samsom, Jan BMJ Jansen and J André Knottnerus
    Citation: BMC Medical Research Methodology 2007 7:16
  28. It is notoriously difficult to recruit patients to randomised controlled trials in primary care. This is particularly true when the disease process under investigation occurs relatively infrequently and must b...

    Authors: Brian McKinstry, Victoria Hammersley, Fergus Daly and Frank Sullivan
    Citation: BMC Medical Research Methodology 2007 7:15
  29. Health surveys provide important information on the burden and secular trends of risk factors and disease. Several factors including survey and item non-response can affect data quality. There are few reports ...

    Authors: Rainford Wilks, Novie Younger, Jasneth Mullings, Namvar Zohoori, Peter Figueroa, Marshall Tulloch-Reid, Trevor Ferguson, Christine Walters, Franklyn Bennett, Terrence Forrester, Elizabeth Ward and Deanna Ashley
    Citation: BMC Medical Research Methodology 2007 7:13
  30. Poor response rates to postal questionnaires can introduce bias and reduce the statistical power of a study. To improve response rates in our trial in primary care we tested the effect of introducing an uncond...

    Authors: Stephen D Brealey, Christine Atwell, Stirling Bryan, Simon Coulton, Helen Cox, Ben Cross, Fiona Fylan, Andrew Garratt, Fiona J Gilbert, Maureen GC Gillan, Maggie Hendry, Kerenza Hood, Helen Houston, David King, Veronica Morton, Jo Orchard…
    Citation: BMC Medical Research Methodology 2007 7:12
  31. In most case control studies the hardest decision is the choice of the control group, as in the ideal control group the proportion exposed is the same as in the population that produced the cases.

    Authors: Odimariles MS Dantas, Ricardo AA Ximenes, Maria de Fatima PM de Albuquerque, Ulisses R Montarroyos, Wayner V de Souza, Patrícia Varejão and Laura C Rodrigues
    Citation: BMC Medical Research Methodology 2007 7:11
  32. Our objective was to develop an instrument to assess the methodological quality of systematic reviews, building upon previous tools, empirical evidence and expert consensus.

    Authors: Beverley J Shea, Jeremy M Grimshaw, George A Wells, Maarten Boers, Neil Andersson, Candyce Hamel, Ashley C Porter, Peter Tugwell, David Moher and Lex M Bouter
    Citation: BMC Medical Research Methodology 2007 7:10
  33. Little is known about the response mechanisms among survivors of disasters. We studied the selective attrition and possible bias in a longitudinal study among survivors of a fireworks disaster.

    Authors: Bellis van den Berg, Peter van der Velden, Rebecca Stellato and Linda Grievink
    Citation: BMC Medical Research Methodology 2007 7:8
  34. To explore the strengths and weaknesses of conventional biomedical research strategies and methods as applied to complementary and alternative medicine (CAM), and to suggest a new research framework for assess...

    Authors: Vinjar Fønnebø, Sameline Grimsgaard, Harald Walach, Cheryl Ritenbaugh, Arne Johan Norheim, Hugh MacPherson, George Lewith, Laila Launsø, Mary Koithan, Torkel Falkenberg, Heather Boon and Mikel Aickin
    Citation: BMC Medical Research Methodology 2007 7:7
  35. Often in survey research, subsets of the population invited to complete the survey do not respond in a timely manner and valuable resources are expended in recontact efforts. Various methods of improving respo...

    Authors: Jean-Paul Chretien, Laura K Chu, Tyler C Smith, Besa Smith and Margaret AK Ryan
    Citation: BMC Medical Research Methodology 2007 7:6
  36. Meta-analysis handles randomized trials with no outcome events in both treatment and control arms inconsistently, including them when risk difference (RD) is the effect measure but excluding them when relative...

    Authors: Jan O Friedrich, Neill KJ Adhikari and Joseph Beyene
    Citation: BMC Medical Research Methodology 2007 7:5
  37. The inclusion of qualitative studies in systematic reviews poses methodological challenges. This paper presents worked examples of two methods of data synthesis (textual narrative and thematic), used in relati...

    Authors: Patricia J Lucas, Janis Baird, Lisa Arai, Catherine Law and Helen M Roberts
    Citation: BMC Medical Research Methodology 2007 7:4
  38. When multiple endpoints are of interest in evidence synthesis, a multivariate meta-analysis can jointly synthesise those endpoints and utilise their correlation. A multivariate random-effects meta-analysis mus...

    Authors: Richard D Riley, Keith R Abrams, Alexander J Sutton, Paul C Lambert and John R Thompson
    Citation: BMC Medical Research Methodology 2007 7:3
  39. This paper describes the study protocol, the recruitment, and base-line data for evaluating the success of randomisation of the PRO-AGE (PRevention in Older people – Assessment in GEneralists' practices) project.

    Authors: Andreas E Stuck, Kalpa Kharicha, Ulrike Dapp, Jennifer Anders, Wolfgang von Renteln-Kruse, Hans Peter Meier-Baumgartner, Steve Iliffe, Danielle Harari, Martin D Bachmann, Matthias Egger, Gerhard Gillmann, John C Beck and Cameron G Swift
    Citation: BMC Medical Research Methodology 2007 7:2
  40. Health risk appraisal is a promising method for health promotion and prevention in older persons. The Health Risk Appraisal for the Elderly (HRA-E) developed in the U.S. has unique features but has not been te...

    Authors: Andreas E Stuck, Kalpa Kharicha, Ulrike Dapp, Jennifer Anders, Wolfgang von Renteln-Kruse, Hans Peter Meier-Baumgartner, Danielle Harari, Cameron G Swift, Katja Ivanova, Matthias Egger, Gerhard Gillmann, Jerilyn Higa, John C Beck and Steve Iliffe
    Citation: BMC Medical Research Methodology 2007 7:1

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