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BMC Medical Research Methodology

Open Access

Erratum to: Statistical methodology for age-adjustment of the GH-2000 score detecting growth hormone misuse

  • Dankmar Böhning1Email author,
  • Walailuck Böhning2,
  • Nishan Guha2, 3,
  • David A. Cowan4,
  • Peter H. Sönksen2 and
  • Richard I. G. Holt2
BMC Medical Research MethodologyBMC series – open, inclusive and trusted201616:164

Published: 28 November 2016

The original article was published in BMC Medical Research Methodology 2016 16:147


After publication of the original article [1], it came to the authors’ attention that there was an error affecting equation (7). A correction to this equation was submitted by the authors during proofing, but was not implemented correctly by the Production team.

The correct version of equation (7) is as follows:
$$ \begin{array}{l}\widehat{\beta^{*}}=\frac{{\displaystyle \sum_{i=1}^n\left({Y}_i^{*}-\overline{Y*}\right)\left({x}_i-\overline{x}\right)}}{{\displaystyle \sum_{i=1}^n{\left({x}_i-\overline{x}\right)}^2}}=\frac{{\displaystyle \sum_{i=1}^n\left({Y}_i-\widehat{\beta}{x}_i-\left(\overline{Y}-\widehat{\beta}\overline{x}\right)\right)}\left({x}_i-\overline{x}\right)}{{\displaystyle \sum_{i=1}^n{\left({x}_i-\overline{x}\right)}^2}}\\ {}\kern2.5em =\frac{{\displaystyle \sum_{i=1}^n\Big({Y}_i-\overline{Y}}\left)\left({x}_i-\overline{x}\right)-\widehat{\beta}{\displaystyle \sum_{i=1}^n\Big({x}_i-\overline{x}}\right){}^2}{{\displaystyle \sum_{i=1}^n{\left({x}_i-\overline{x}\right)}^2}}\\ {}\kern2.5em =\frac{{\displaystyle \sum_{i=1}^n\Big({Y}_i-}\overline{Y}\Big)\left({x}_i-\overline{x}\right)}{{\displaystyle \sum_{i=1}^n{\left({x}_i-\overline{x}\right)}^2}}-\widehat{\beta}\frac{{\displaystyle \sum_{i=1}^n\Big(}{x}_i-\overline{x}\Big){}^2}{{\displaystyle \sum_{i=1}^n{\left({x}_i-\overline{x}\right)}^2}}=0.\end{array} $$

Equation (7) has also been updated in the original article in order to rectify this publisher’s error.



Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

Authors’ Affiliations

Southampton Statistical Sciences Research Institute, University of Southampton, Southampton, UK
Human Development and Health Academic Unit, University of Southampton Faculty of Medicine, IDS Building (MP887), Southampton General Hospital, Southampton, UK
Nuffield Division of Clinical Laboratory Sciences, UK Department of Clinical Biochemistry Level 4, University of Oxford, Oxford, UK
Department of Pharmacy and Forensic Science, Drug Control Centre, King’s College London, London, UK


  1. Böhning D, Böhning W, Guha N, Cowan DA, Sönksen PH, Holt RI. Statistical methodology for age-adjustment of the GH-2000 score detecting growth hormone misuse. BMC Med Res Methodol. 2016;16:147. doi:10.1186/s12874-016-0246-8.View ArticlePubMedPubMed CentralGoogle Scholar


© The Author(s). 2016