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  1. The effect of timing of incentive payments on the response rate of telephone surveys is unknown. This study examined whether up-front or delayed incentive payments were associated with higher response rates fo...

    Authors: Weng-Yee Chin, Edmond PH Choi and Cindy LK Lam
    Citation: BMC Medical Research Methodology 2015 15:79
    Content type: Research article Published on:

  2. Health examination surveys (HESs), carried out in Europe since the 1950’s, provide valuable information about the general population’s health for health monitoring, policy making, and research. Survey particip...

    Authors: Jennifer S. Mindell, Simona Giampaoli, Antje Goesswald, Panagiotis Kamtsiuris, Charlotte Mann, Satu Männistö, Karen Morgan, Nicola J. Shelton, WM Monique Verschuren and Hanna Tolonen
    Citation: BMC Medical Research Methodology 2015 15:78
    Content type: Research article Published on:

  3. Developing valid and reliable patient-reported outcome measures (PROMs) is a critical step in promoting patient-centered health care, a national priority in the U.S. Small populations or rare diseases often po...

    Authors: Lili Garrard, Larry R. Price, Marjorie J. Bott and Byron J. Gajewski
    Citation: BMC Medical Research Methodology 2015 15:77
    Content type: Research article Published on:

  5. The initial vanguard cohort of the U.S. National Children’s Study was a pregnancy and birth cohort study that sought to enroll some women prior to pregnancy, and to assess exposures early in pregnancy.

    Authors: Joseph B. Stanford, Ruth Brenner, David Fetterer, Leslie Palmer and Kenneth C. Schoendorf
    Citation: BMC Medical Research Methodology 2015 15:75
    Content type: Research article Published on:

  6. With increasing attention put on the methodology of reporting guidelines, Moher et al. conducted a review of reporting guidelines up to December 2009. Information gaps appeared on many aspects. Therefore, in 2...

    Authors: Xiaoqin Wang, Yaolong Chen, Nan Yang, Wei Deng, Qi Wang, Nan Li, Liang Yao, Dang Wei, Gen Chen and Kehu Yang
    Citation: BMC Medical Research Methodology 2015 15:74
    Content type: Research article Published on:

  7. Several papers report deficiencies in the reporting of information about the implementation of interventions in clinical trials. Information about implementation is also required in systematic reviews of compl...

    Authors: Margaret Cargo, Ivana Stankov, James Thomas, Michael Saini, Patricia Rogers, Evan Mayo-Wilson and Karin Hannes
    Citation: BMC Medical Research Methodology 2015 15:73
    Content type: Research article Published on:

  9. Automatic stepwise subset selection methods in linear regression often perform poorly, both in terms of variable selection and estimation of coefficients and standard errors, especially when number of independ...

    Authors: Olga Morozova, Olga Levina, Anneli Uusküla and Robert Heimer
    Citation: BMC Medical Research Methodology 2015 15:71
    Content type: Research article Published on:

  12. The implementation of strategies to monitor and enhance treatment fidelity is of paramount importance in trials of complex interventions. A recent framework published by the National Institutes of Health Behavior...

    Authors: Brigit M. Chesworth, Michael J. Leathley, Lois H. Thomas, Christopher J. Sutton, Denise Forshaw and Caroline L. Watkins
    Citation: BMC Medical Research Methodology 2015 15:68
    Content type: Research article Published on:

  13. A public-private (51/49 %) partnership was initiated in 2007 in France to improve the attractiveness of French sites in industry-sponsored international clinical trials. This initiative developed and implement...

    Authors: Régis Bordet, Marie Lang, Christelle Dieu, Nathalie Billon and Jean-Pierre Duffet
    Citation: BMC Medical Research Methodology 2015 15:67
    Content type: Research article Published on:

  14. Previous research has shown that the personalisation of study invitations improves response rates in survey-based research. To examine if this finding extends to experimental studies, we examined the impact of...

    Authors: Camille E. Short, Amanda L. Rebar and Corneel Vandelanotte
    Citation: BMC Medical Research Methodology 2015 15:66
    Content type: Correspondence Published on:

    The Erratum to this article has been published in BMC Medical Research Methodology 2015 15:102

  15. Skeletal related events (SREs) are common in men with metastatic prostate cancer (mPC). Various methods have been used to identify SREs from claims data. The objective of this study was to provide a framework ...

    Authors: Abdalla Aly, Eberechukwu Onukwugha, Corinne Woods, C. Daniel Mullins, Young Kwok, Yi Qian, Jorge Arellano, Arun Balakumaran and Arif Hussain
    Citation: BMC Medical Research Methodology 2015 15:65
    Content type: Research article Published on:

  18. Proxy responses are very common when surveys are conducted among the elderly or disabled population. Outcomes reported by proxy may be systematically different from those obtained from patients directly. The o...

    Authors: Minghui Li, Ilene Harris and Z. Kevin Lu
    Citation: BMC Medical Research Methodology 2015 15:62
    Content type: Research article Published on:

  19. When conducting a meta-analysis of a continuous outcome, estimated means and standard deviations from the selected studies are required in order to obtain an overall estimate of the mean effect and its confide...

    Authors: Deukwoo Kwon and Isildinha M. Reis
    Citation: BMC Medical Research Methodology 2015 15:61
    Content type: Research article Published on:

  20. The Godin-Shephard Leisure-Time Physical Activity Questionnaire (GSLTPAQ) is one of the most often used questionnaires in oncology research, yet modifications to the scale are done with little evidence of psyc...

    Authors: Steve Amireault, Gaston Godin, Jason Lacombe and Catherine M. Sabiston
    Citation: BMC Medical Research Methodology 2015 15:60
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Medical Research Methodology 2016 16:30

  21. Clustered data with binary outcomes are often analysed using random intercepts models or generalised estimating equations (GEE) resulting in cluster-specific or ‘population-average’ inference, respectively.

    Authors: Menelaos Pavlou, Gareth Ambler, Shaun Seaman and Rumana Z. Omar
    Citation: BMC Medical Research Methodology 2015 15:59
    Content type: Technical advance Published on:

  23. A major challenge in updating clinical guidelines is to efficiently identify new, relevant evidence. We evaluated the efficiency and feasibility of two new approaches: the development of restrictive search str...

    Authors: L. Martínez García, AJ. Sanabria, I. Araya, J. Lawson, I. Solà, RWM. Vernooij, D. López, E. García Álvarez, MM. Trujillo-Martín, I. Etxeandia-Ikobaltzeta, A. Kotzeva, D. Rigau, A. Louro-González, L. Barajas-Nava, P. Díaz del Campo, MD. Estrada…
    Citation: BMC Medical Research Methodology 2015 15:57
    Content type: Research article Published on:

  24. An increasing number of research designs are using text messaging (SMS) as a means of self-reported symptom and outcome monitoring in a variety of long-term health conditions, including severity ratings of dep...

    Authors: Ada Keding, Jan R. Böhnke, Tim J. Croudace, Stewart J. Richmond and Hugh MacPherson
    Citation: BMC Medical Research Methodology 2015 15:56
    Content type: Research article Published on:

  25. Multi-item questionnaires are important instruments for monitoring health in epidemiological longitudinal studies. Mostly sum-scores are used as a summary measure for these multi-item questionnaires. The objec...

    Authors: Rosalie Gorter, Jean-Paul Fox and Jos W. R. Twisk
    Citation: BMC Medical Research Methodology 2015 15:55
    Content type: Research article Published on:

  26. Estimations of survival rates are diverse and the choice of the appropriate method depends on the context. Given the increasing interest in multiple imputation methods, we explored the interest of a multiple i...

    Authors: Adeline Morisot, Faïza Bessaoud, Paul Landais, Xavier Rébillard, Brigitte Trétarre and Jean-Pierre Daurès
    Citation: BMC Medical Research Methodology 2015 15:54
    Content type: Research Article Published on:

  27. Propensity score methods have become a popular tool for reducing selection bias in making causal inference from observational studies in medical research. Propensity score matching, a key component of propensi...

    Authors: Wei Pan and Haiyan Bai
    Citation: BMC Medical Research Methodology 2015 15:53
    Content type: Research article Published on:

  28. Attrition is an important problem in cohort studies. Tracing cohort members who have moved or otherwise lost contact with the study is vital. There is some debate about the acceptability and relative effective...

    Authors: Isabelle Bray, Sian Noble, Andy Boyd, Lindsey Brown, Pei Hayes, Joanne Malcolm, Ross Robinson, Rachel Williams, Kirsty Burston, John Macleod, Lynn Molloy and Kate Tilling
    Citation: BMC Medical Research Methodology 2015 15:52
    Content type: Research article Published on:

  29. The purpose of this note is to contribute some general points on a recent paper by Ledberg and Wennberg (BMC Med Res Meth 14:58, 2014) which need to be rectified. They advocate the capture-removal estimator. F...

    Authors: Dankmar Böhning and Peter G.M. van der Heijden
    Citation: BMC Medical Research Methodology 2015 15:51
    Content type: CORRESPONDENCE Published on:

    The Erratum to this article has been published in BMC Medical Research Methodology 2015 15:76

  30. The results of multivariable regression models are usually summarized in the form of parameter estimates for the covariates, goodness-of-fit statistics, and the relevant p-values. These statistics do not infor...

    Authors: Babak Choodari-Oskooei, Patrick Royston and Mahesh K.B. Parmar
    Citation: BMC Medical Research Methodology 2015 15:50
    Content type: Research Article Published on:

  32. Simon’s two-stage designs are popular choices for conducting phase II clinical trials, especially in the oncology trials to reduce the number of patients placed on ineffective experimental therapies. Recently ...

    Authors: Junjun Zhao, Menggang Yu and Xi-Ping Feng
    Citation: BMC Medical Research Methodology 2015 15:48
    Content type: Research Article Published on:

  34. Record linkage of existing individual health care data is an efficient way to answer important epidemiological research questions. Reuse of individual health-related data faces several problems: Either a uniqu...

    Authors: Kurt Schmidlin, Kerri M. Clough-Gorr and Adrian Spoerri
    Citation: BMC Medical Research Methodology 2015 15:46
    Content type: Research article Published on:

  35. Comparing the relative utility of diagnostic tests is challenging when available datasets are small, partial or incomplete. The analytical leverage associated with a large sample size can be gained by integrat...

    Authors: Vivienne Breen, Nikola Kasabov, Ashish M. Kamat, Elsie Jacobson, James M. Suttie, Paul J. O’Sullivan, Laimonis Kavalieris and David G. Darling
    Citation: BMC Medical Research Methodology 2015 15:45
    Content type: Research article Published on:

  36. With the increase of clinical trial costs during the last decades, the design of feasibility studies has become an essential process to reduce avoidable and costly protocol amendments. This design includes tim...

    Authors: Iñaki Soto-Rey, Benjamin Trinczek, Yannick Girardeau, Eric Zapletal, Nadir Ammour, Justin Doods, Martin Dugas and Fleur Fritz
    Citation: BMC Medical Research Methodology 2015 15:44
    Content type: Research article Published on:

  38. When summary results from studies of counts of events in time contain zeros, the study-specific incidence rate ratio (IRR) and its standard error cannot be calculated because the log of zero is undefined. This...

    Authors: Matthew J Spittal, Jane Pirkis and Lyle C Gurrin
    Citation: BMC Medical Research Methodology 2015 15:42
    Content type: Research Article Published on:

  39. Informed consent is the foundation of the ethical conduct of health research. Obtaining informed consent may unwittingly interfere with the data collected in research studies, particularly if they concern sens...

    Authors: Lambert Felix, Patrick Keating and Jim McCambridge
    Citation: BMC Medical Research Methodology 2015 15:41
    Content type: Research article Published on:

  41. Cancer incidence and prevalence estimates are necessary to inform health policy, to predict public health impact and to identify etiological factors. Registers have been used to estimate the number of cancer c...

    Authors: Laurent Bailly, Jean Pierre Daurès, Brigitte Dunais and Christian Pradier
    Citation: BMC Medical Research Methodology 2015 15:39
    Content type: Research article Published on:

  42. Small number of clusters and large variation of cluster sizes commonly exist in cluster-randomized trials (CRTs) and are often the critical factors affecting the validity and efficiency of statistical analyses. F

    Authors: Peng Li and David T Redden
    Citation: BMC Medical Research Methodology 2015 15:38
    Content type: Research article Published on:

  43. In many medical studies the likelihood ratio test (LRT) has been widely applied to examine whether the random effects variance component is zero within the mixed effects models framework; whereas little work a...

    Authors: Ping Zeng, Yang Zhao, Hongliang Li, Ting Wang and Feng Chen
    Citation: BMC Medical Research Methodology 2015 15:37
    Content type: Research article Published on:

  46. Network meta-analysis (NMA) is a methodology for indirectly comparing, and strengthening direct comparisons of two or more treatments for the management of disease by combining evidence from multiple studies. ...

    Authors: Howard HZ Thom, Gorana Capkun, Annamaria Cerulli, Richard M Nixon and Luke S Howard
    Citation: BMC Medical Research Methodology 2015 15:34
    Content type: Research article Published on:

  47. Accurate blood pressure measurements are needed in clinical practice, intervention studies and health examination surveys. Blood pressure measurements are sensitive: their accuracy can be affected by measureme...

    Authors: Hanna Tolonen, Päivikki Koponen, Androniki Naska, Satu Männistö, Grazyna Broda, Tarja Palosaari and Kari Kuulasmaa
    Citation: BMC Medical Research Methodology 2015 15:33
    Content type: Research article Published on:

  48. Survey research in healthcare is an important tool to collect information about healthcare delivery, service use and overall issues relating to quality of care. Unfortunately, physicians are often a group with...

    Authors: Ceara Tess Cunningham, Hude Quan, Brenda Hemmelgarn, Tom Noseworthy, Cynthia A Beck, Elijah Dixon, Susan Samuel, William A Ghali, Lindsay L Sykes and Nathalie Jetté
    Citation: BMC Medical Research Methodology 2015 15:32
    Content type: Research article Published on:

  49. In resource-limited settings, monitoring and evaluation (M&E) of antiretroviral treatment (ART) programs often relies on aggregated facility-level data. Such data are limited, however, because of the potential...

    Authors: Sebastien Haneuse, Bethany Hedt-Gauthier, Frank Chimbwandira, Simon Makombe, Lyson Tenthani and Andreas Jahn
    Citation: BMC Medical Research Methodology 2015 15:31
    Content type: Research article Published on:

  50. Missing data are common in medical research, which can lead to a loss in statistical power and potentially biased results if not handled appropriately. Multiple imputation (MI) is a statistical method, widely ...

    Authors: Panteha Hayati Rezvan, Katherine J Lee and Julie A Simpson
    Citation: BMC Medical Research Methodology 2015 15:30
    Content type: Research article Published on:
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BMC Medical Research Methodology

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