Dakin HA, Gray A. Economic evaluation of factorial randomised controlled trials: challenges, methods and recommendations. Stat Med. 2017;36(18):2814–30.
Dakin HA, Gray A. Decision-making for healthcare resource allocation: joint versus separate decisions on interacting interventions. Med Decis Mak. 2018;38(4):476–86.
Hung HM, Chi GY, O'Neill RT. Efficacy evaluation for monotherapies in two-by-two factorial trials. Biometrics. 1995;51(4):1483–93.
Hung HM. Two-stage tests for studying monotherapy and combination therapy in two-by-two factorial trials. Stat Med. 1993;12(7):645–60.
Montgomery AA, Peters TJ, Little P. Design, analysis and presentation of factorial randomised controlled trials. BMC Med Res Methodol. 2003;3:26.
Brittain E, Wittes J. Factorial designs in clinical trials: the effects of non-compliance and subadditivity. Stat Med. 1989;8(2):161–71.
Green S. Factorial designs with time to event endpoints. In: Crowley J, Ankerst DP, editors. Handbook of Statistics in Clinical Oncology. 2nd ed. Boca Raton: Chapman & Hall/CRC; 2006. p. 181–9.
Claxton K. The irrelevance of inference: a decision-making approach to the stochastic evaluation of health care technologies. J Health Econ. 1999;18(3):341–64.
Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med. 2009;6(7):e1000100.
McAlister FA, Straus SE, Sackett DL, Altman DG. Analysis and reporting of factorial trials: a systematic review. JAMA. 2003;289(19):2545–53.
Brown J, Welton NJ, Bankhead C, Richards SH, Roberts L, Tydeman C, Peters TJ. A Bayesian approach to analysing the cost-effectiveness of two primary care interventions aimed at improving attendance for breast screening. Health Econ. 2006;15(5):435–45.
Welton NJ, Ades AE, Caldwell DM, Peters TJ. Research prioritization based on expected value of partial perfect information: a case-study on interventions to increase uptake of breast cancer screening. J R Statist Soc A. 2008;171(Part 4):807–41.
Welton NJ, Madan JJ, Caldwell DM, Peters TJ, Ades AE. Expected value of sample information for multi-arm cluster randomized trials with binary outcomes. Med Decis Mak. 2013;34:352–65.
National Institute for Health and Care Excellence (NICE). Guide to the methods of technology appraisal 2013. https://www.nice.org.uk/process/pmg9/chapter/foreword. Accessed 16 Apr 2020.
UK Beam Trial Team. United Kingdom back pain exercise and manipulation (UK BEAM) randomised trial: cost effectiveness of physical treatments for back pain in primary care. BMJ. 2004;329(7479):1381.
Boyle J, McCartney E, Forbes J, O'Hare A: A randomised controlled trial and economic evaluation of direct versus indirect and individual versus group modes of speech and language therapy for children with primary language impairment. Health Technol Assess. 2007;11(25):iii-iv, xi-xii, 1–139.
Hollinghurst S, Sharp D, Ballard K, Barnett J, Beattie A, Evans M, Lewith G, Middleton K, Oxford F, Webley F, et al. Randomised controlled trial of Alexander technique lessons, exercise, and massage (ATEAM) for chronic and recurrent back pain: economic evaluation. BMJ. 2008;337:a2656.
Reddy P, Kalus JS, Caron MF, Horowitz S, Karapanos A, Coleman CI, Kluger J, White CM. Economic analysis of intravenous plus oral amiodarone, atrial septal pacing, and both strategies to prevent atrial fibrillation after open heart surgery. Pharmacotherapy. 2004;24(8):1013–9.
Foster EM, Jensen PS, Schlander M, Pelham WE Jr, Hechtman L, Arnold LE, Swanson JM, Wigal T. Treatment for ADHD: is more complex treatment cost-effective for more complex cases? Health Serv Res. 2007;42(1 Pt 1):165–82.
Hollis JF, McAfee TA, Fellows JL, Zbikowski SM, Stark M, Riedlinger K. The effectiveness and cost effectiveness of telephone counselling and the nicotine patch in a state tobacco quitline. Tobacco Control. 2007;16(Supplement(1)):i53–9.
StataCorp: sureg — Zellner’s seemingly unrelated regression. In: Stata Base Reference Manual: Release 11. Volume Volume 3, Q-Z, edn. College Station: StataCorp LP; 2009: 2100–2107.
Ng T. The impact of a preliminary test for interaction in a 2 x 2 factorial trial. Proc Biopharmaceutical Sec Am Stat Assoc Alexandria. 1991:220–7.
Simon R, Freedman LS. Bayesian design and analysis of two x two factorial clinical trials. Biometrics. 1997;53(2):456–64.
Briggs A. Economic evaluation and clinical trials: size matters. Bmj. 2000;321(7273):1362–3.
Backhouse ME. Use of randomised controlled trials for producing cost-effectiveness evidence: potential impact of design choices on sample size and study duration. Pharmacoeconomics. 2002;20(15):1061–77.
Ramsey S, Willke R, Briggs A, Brown R, Buxton M, Chawla A, Cook J, Glick H, Liljas B, Petitti D, et al. Good research practices for cost-effectiveness analysis alongside clinical trials: the ISPOR RCT-CEA task force report. Value Health. 2005;8(5):521–33.
Hollingworth W, McKell-Redwood D, Hampson L, Metcalfe C: Cost utility analysis conducted alongside RCTs: is inefficiency considered in sample size calculations? Poster presented at the MRC Clinical Trials Methodology Conference, Bristol, UK, 4th–5th October 2011 2011.
Anderson P, Lloyd A. Outcomes research and health economics. In: Di Giovanna I, Hayes G, editors. Principles of Clinical Research. Stroud: Wrightson Biomedical Publishing Ltd; 2001. p. 291–316.
Marshall DA, Hux M. Design and analysis issues for economic analysis alongside clinical trials. Med Care. 2009;47(7 Suppl 1):S14–20.
O'Brien B. Economic evaluation of pharmaceuticals. Frankenstein's monster or vampire of trials? Med Care. 1996;34(12 Suppl):DS99–108.
Byar DP. Factorial and reciprocal control designs. Stat Med. 1990;9(1–2):55–63 discussion 63-54.
Byar DP, Piantadosi S. Factorial designs for randomized clinical trials. Cancer Treat Rep. 1985;69(10):1055–63.
Yates F. Complex experiments (with discussion). J Roy Statist Soc. 1935;B2:181–247.
Burnham KP, Anderson DR. Multimodel inference: understanding AIC and BIC in model selection. Sociol Methods Res. 2004;33(2):261–304.
Lancelot R, Lesnoff M, McDermott JJ. Use of Akaike information criteria for model selection and inference: an application to assess prevention of gastrointestinal parasitism and respiratory mortality of Guinean goats in Kolda, Senegal. Preventive Veterinary Med. 2002;55(4):217–40.
Piantadosi S. Chapter 19: factorial trials. In: Clinical trials: a methodological perspective. 2nd ed. Hoboken: Wiley; 2005. p. 501–13.
Frempong SN, Goranitis I, Oppong R. Economic evaluation alongside factorial trials: a systematic review of empirical studies. Expert Rev Pharmacoecon Outcomes Res. 2015;15(5):801–11.
Campbell AJ, Robertson MC, La Grow SJ, Kerse NM, Sanderson GF, Jacobs RJ, Sharp DM, Hale LA. Randomised controlled trial of prevention of falls in people aged >=75 with severe visual impairment: the VIP trial. BMJ. 2005;331(7520):817.
Sevick MA, Miller GD, Loeser RF, Williamson JD, Messier SP. Cost-effectiveness of exercise and diet in overweight and obese adults with knee osteoarthritis. Med Sci Sports Exerc. 2009;41(6):1167–74.
Salize HJP, Merkel SD-R, Reinhard ID-M, Twardella DP, Mann KMD, Brenner HMDMPH. Cost-effective primary care-based strategies to improve smoking cessation: more value for money. Arch Intern Med. 2009;169(3):230–5.
Lamb SE, Gates S, Underwood MR, Cooke MW, Ashby D, Szczepura A, Williams MA, Williamson EM, Withers EJ, Mt Isa S, et al. Managing injuries of the neck trial (MINT): design of a randomised controlled trial of treatments for whiplash associated disorders. BMC Musculoskelet Disord. 2007;8:7.
Thorn JC, Ridyard CH, Hughes D, Wordsworth S, Mihaylova B, Noble S, Hollingworth W. Health economics analysis plans: where are we now? Value Health. 2016;19(7):A397.
Dakin HA, Wordsworth S, Rogers CA, Abangma G, Raftery J, Harding SP, Lotery AJ, Downes SM, Chakravarthy U, Reeves BC, et al. Cost-effectiveness of ranibizumab and bevacizumab for age-related macular degeneration: 2-year findings from the IVAN randomised trial. BMJ Open. 2014;4(7):e005094.