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  1. For practical reasons it is not easy to obtain fasting samples in large population health surveys. Non-fasting triglyceride (Tg) values are difficult to interpret. The authors compared the accuracy of statisti...

    Authors: Jouko Sundvall, Jaana Leiviskä, Tiina Laatikainen, Markku Peltonen, Veikko Salomaa, Mauno Vanhala, Eeva Korpi-Hyövälti, Jukka Lauronen and Georg Alfthan
    Citation: BMC Medical Research Methodology 2011 11:63
  2. Minimising participant non-response in postal surveys helps to maximise the generalisability of the inferences made from the data collected. The aim of this study was to examine the effect of questionnaire len...

    Authors: Shannon Sahlqvist, Yena Song, Fiona Bull, Emma Adams, John Preston and David Ogilvie
    Citation: BMC Medical Research Methodology 2011 11:62
  3. Ambulatory blood pressure monitoring (ABPM) is increasingly used to measure blood pressure (BP) in research studies. We examined ease of use, comfort, degree of disturbance, reported adverse effects, factors a...

    Authors: Anthony J Viera, Kara Lingley and Alan L Hinderliter
    Citation: BMC Medical Research Methodology 2011 11:59
  4. Mixed effects logistic models have become a popular method for analyzing multicenter clinical trials with binomial data. However, the statistical properties of these models for testing homogeneity of odds rati...

    Authors: Zahra Bagheri, Seyyed Mohammad Taghi Ayatollahi and Peyman Jafari
    Citation: BMC Medical Research Methodology 2011 11:58
  5. Health related quality of life (HRQOL) has increasingly emphasized on cancer patients. The psychometric properties of the standard Chinese version of the European Organization for Research and Treatment of Can...

    Authors: Jin-xiang Cheng, Bo-lin Liu, Xiang Zhang, Yong-qiang Zhang, Wei Lin, Rui Wang, Yong-qin Zhang, Hong-ying Zhang, Li Xie and Jun-li Huo
    Citation: BMC Medical Research Methodology 2011 11:56
  6. Intention-to-treat (ITT) is the standard data analysis method which includes all patients regardless of receiving treatment. Although the aim of ITT analysis is to prevent bias due to prognostic dissimilarity,...

    Authors: Branko Miladinovic, Ambuj Kumar, Iztok Hozo and Benjamin Djulbegovic
    Citation: BMC Medical Research Methodology 2011 11:55
  7. During community epidemics, infections may be imported within hospital and transmitted to hospitalized patients. Hospital outbreaks of communicable diseases have been increasingly reported during the last deca...

    Authors: Nicolas Voirin, Sylvain Roche, Philippe Vanhems, Marine Giard, Sandra David-Tchouda, Béatrice Barret and René Ecochard
    Citation: BMC Medical Research Methodology 2011 11:53
  8. Currently, there is one Behçet's disease (BD) specific self reporting questionnaire developed and published in the literature, The Leeds BD-quality of life (QoL). We conducted a cross-cultural adaptation and v...

    Authors: Zahi Touma, Lilian Ghandour, Abla Sibai, Houry Puzantian, Ayad Hamdan, Omar Hamdan, Jeanine Menassa, Imad Uthman and Thurayya Arayssi
    Citation: BMC Medical Research Methodology 2011 11:52
  9. Previous research has documented heterogeneity in the effects of maternal education on adverse birth outcomes by nativity and Hispanic subgroup in the United States. In this article, we considered the risk of ...

    Authors: Jay S Kaufman, Richard F MacLehose, Elizabeth A Torrone and David A Savitz
    Citation: BMC Medical Research Methodology 2011 11:51
  10. Many studies compared the degree of concordance between adolescents' and parents' reports on family socioeconomic status (SES). However, none of these studies analyzed whether the degree of concordance varies ...

    Authors: Christy Pu, Nicole Huang and Yiing-Jenq Chou
    Citation: BMC Medical Research Methodology 2011 11:50
  11. Many previous studies have found seasonal patterns in birth outcomes, but with little agreement about which season poses the highest risk. Some of the heterogeneity between studies may be explained by a previo...

    Authors: Linn Beate Strand, Adrian G Barnett and Shilu Tong
    Citation: BMC Medical Research Methodology 2011 11:49
  12. Alcohol is a major risk factor for burden of disease and injuries globally. This paper presents a systematic method to compute the 95% confidence intervals of alcohol-attributable fractions (AAFs) with exposur...

    Authors: Gerrit Gmel, Kevin D Shield, Hannah Frick, Tara Kehoe, Gerhard Gmel and Jürgen Rehm
    Citation: BMC Medical Research Methodology 2011 11:48
  13. To develop a web-based computer adaptive testing (CAT) application for efficiently collecting data regarding workers' perceptions of job satisfaction, we examined whether a 37-item Job Content Questionnaire (J...

    Authors: Tsair-Wei Chien, Wen-Pin Lai, Chih-Wei Lu, Weng-Chung Wang, Shih-Chung Chen, Hsien-Yi Wang and Shih-Bin Su
    Citation: BMC Medical Research Methodology 2011 11:47
  14. Defining what constitutes a resident care unit in nursing home research is both a conceptual and practical challenge. The aim of this paper is to provide evidence in support of a definition of care unit in nursin...

    Authors: Carole A Estabrooks, Debra G Morgan, Janet E Squires, Anne-Marie Boström, Susan E Slaughter, Greta G Cummings and Peter G Norton
    Citation: BMC Medical Research Methodology 2011 11:46
  15. Estimating costs is essential to the economic analysis of health care programs. Health care costs are often captured from administrative databases or by patient report. Administrative records only provide a pa...

    Authors: Daniel Pinto, M Clare Robertson, Paul Hansen and J Haxby Abbott
    Citation: BMC Medical Research Methodology 2011 11:45
  16. The number of events per individual is a widely reported variable in medical research papers. Such variables are the most common representation of the general variable type called discrete numerical. There is ...

    Authors: Morten W Fagerland, Leiv Sandvik and Petter Mowinckel
    Citation: BMC Medical Research Methodology 2011 11:44
  17. Workflow engine technology represents a new class of software with the ability to graphically model step-based knowledge. We present application of this novel technology to the domain of clinical decision supp...

    Authors: Vojtech Huser, Luke V Rasmussen, Ryan Oberg and Justin B Starren
    Citation: BMC Medical Research Methodology 2011 11:43
  18. Cohort studies can provide valuable evidence of cause and effect relationships but are subject to loss of participants over time, limiting the validity of findings. Computerised record linkage offers a passive...

    Authors: Alison Beauchamp, Andrew M Tonkin, Helen Kelsall, Vijaya Sundararajan, Dallas R English, Lalitha Sundaresan, Rory Wolfe, Gavin Turrell, Graham G Giles and Anna Peeters
    Citation: BMC Medical Research Methodology 2011 11:42
  19. Clinical researchers have often preferred to use a fixed effects model for the primary interpretation of a meta-analysis. Heterogeneity is usually assessed via the well known Q and I 2 statistics, along with the ...

    Authors: Jack Bowden, Jayne F Tierney, Andrew J Copas and Sarah Burdett
    Citation: BMC Medical Research Methodology 2011 11:41
  20. A prospective cohort study was set up to investigate a possible association between antibiotic prescribing and antibiotic resistance of E. coli urinary tract infection in the community. Participation of patients ...

    Authors: Akke Vellinga, Martin Cormican, Belinda Hanahoe, Kathleen Bennett and Andrew W Murphy
    Citation: BMC Medical Research Methodology 2011 11:40
  21. The primary aim of this study was to provide an estimate of effect size for the functional outcome of operative versus non-operative treatment for patients with an acute rupture of the Achilles tendon using ac...

    Authors: Rebecca S Kearney, Juul Achten, Nick R Parsons and Matthew L Costa
    Citation: BMC Medical Research Methodology 2011 11:39
  22. Despite the importance of collecting individual data of socioeconomic status (SES) in epidemiological oral health surveys with children, this procedure relies on the parents as respondents. Therefore, type of ...

    Authors: Chaiana Piovesan, Monica Carneiro Pádua, Thiago Machado Ardenghi, Fausto Medeiros Mendes and Gabriela Cunha Bonini
    Citation: BMC Medical Research Methodology 2011 11:37
  23. There has been little research on design of studies based on routinely collected data when the clinical endpoint of interest is not recorded, but can be inferred from a prescription. This often happens when ex...

    Authors: Sara Lodi, James Carpenter, Peter Egger and Stephen Evans
    Citation: BMC Medical Research Methodology 2011 11:36
  24. Recruitment of patients by health professionals is reported as one of the most challenging steps when undertaking studies in primary care settings. Numerous investigations of the barriers to patient recruitmen...

    Authors: Matthew J Page, Simon D French, Joanne E McKenzie, Denise A O'Connor and Sally E Green
    Citation: BMC Medical Research Methodology 2011 11:35
  25. Observational studies, if conducted appropriately, play an important role in the decision-making process providing invaluable information on effectiveness, patient-reported outcomes and costs in a real-world e...

    Authors: Sue Langham, Julia Langham, Hans-Peter Goertz and Mark Ratcliffe
    Citation: BMC Medical Research Methodology 2011 11:32
  26. Purchasers can play an important role in eliminating racial and ethnic disparities in health care. A need exists to develop a compelling "business case" from the employer perspective to put, and keep, the issu...

    Authors: David R Nerenz, Yung-wen Liu, Keoki L Williams, Kaan Tunceli and Huiwen Zeng
    Citation: BMC Medical Research Methodology 2011 11:31
  27. This study aimed to evaluate the reliability and validity of two self-report physical activity (PA) questionnaires - the AQuAA (Activity Questionnaire for Adults and Adolescents) and PASE (Physical Activity Sc...

    Authors: Roberto DK Liu, Laurien M Buffart, Marie José Kersten, Marjolein Spiering, Johannes Brug, Willem van Mechelen and Mai JM Chinapaw
    Citation: BMC Medical Research Methodology 2011 11:30
  28. A variety of different approaches to the synthesis of qualitative data are advocated in the literature. The aim of this paper is to describe the application of a pragmatic method of qualitative evidence synthe...

    Authors: Christopher Carroll, Andrew Booth and Katy Cooper
    Citation: BMC Medical Research Methodology 2011 11:29
  29. The last decade has seen a number of methodological developments in meta-analysis of diagnostic test studies. However, it is unclear whether such developments have permeated the wider research community and on...

    Authors: Brian H Willis and Muireann Quigley
    Citation: BMC Medical Research Methodology 2011 11:27
  30. Administrative health care databases offer an efficient and accessible, though as-yet unvalidated, approach to studying outcomes of patients with chronic kidney disease and end-stage renal disease (ESRD). The ...

    Authors: Fiona M Clement, Matthew T James, Rick Chin, Scott W Klarenbach, Braden J Manns, Robert R Quinn, Pietro Ravani, Marcello Tonelli and Brenda R Hemmelgarn
    Citation: BMC Medical Research Methodology 2011 11:25
  31. The development, implementation and evaluation of any new health intervention is complex. This paper uses experiences from the design, implementation and evaluation of a rehabilitation programme to shed light ...

    Authors: Lydia Bird, Antony Arthur and Karen Cox
    Citation: BMC Medical Research Methodology 2011 11:24
  32. Clinical practice guidelines are an important element of evidence-based practice. Considering an often complicated body of evidence can be problematic for guideline developers, who in the past may have resorte...

    Authors: Susan Hillier, Karen Grimmer-Somers, Tracy Merlin, Philippa Middleton, Janet Salisbury, Rebecca Tooher and Adele Weston
    Citation: BMC Medical Research Methodology 2011 11:23
  33. Dealing with heterogeneity in meta-analyses is often tricky, and there is only limited advice for authors on what to do. We investigated how authors addressed different degrees of heterogeneity, in particular ...

    Authors: Jeppe B Schroll, Rasmus Moustgaard and Peter C Gøtzsche
    Citation: BMC Medical Research Methodology 2011 11:22
  34. Multicentre randomized controlled trials (RCTs) routinely use randomization and analysis stratified by centre to control for differences between centres and to improve precision. No consensus has been reached ...

    Authors: Rong Chu, Lehana Thabane, Jinhui Ma, Anne Holbrook, Eleanor Pullenayegum and Philip James Devereaux
    Citation: BMC Medical Research Methodology 2011 11:21
  35. Collecting population data on sensitive issues such as non-suicidal self-injury (NSSI) is problematic. Case note audits or hospital/clinic based presentations only record severe cases and do not distinguish be...

    Authors: Anne W Taylor, Graham Martin, Eleonora Dal Grande, Sarah Swannell, Simon Fullerton, Philip Hazell and James E Harrison
    Citation: BMC Medical Research Methodology 2011 11:20
  36. Attrition, which leads to missing data, is a common problem in cluster randomized trials (CRTs), where groups of patients rather than individuals are randomized. Standard multiple imputation (MI) strategies ma...

    Authors: Jinhui Ma, Noori Akhtar-Danesh, Lisa Dolovich and Lehana Thabane
    Citation: BMC Medical Research Methodology 2011 11:18
  37. Many research projects in general practice face problems when recruiting patients, often resulting in low recruitment rates and an unknown selection bias, thus limiting their value for health services research...

    Authors: Stephanie Heinemann, Sabine Thüring, Sven Wedeken, Tobias Schäfer, Christa Scheidt-Nave, Mirko Ketterer and Wolfgang Himmel
    Citation: BMC Medical Research Methodology 2011 11:16
  38. Hundreds of studies of maternity care interventions have been published, too many for most people involved in providing maternity care to identify and consider when making decisions. It became apparent that sy...

    Authors: Valerie Smith, Declan Devane, Cecily M Begley and Mike Clarke
    Citation: BMC Medical Research Methodology 2011 11:15

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