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  1. Familism and parental respect are culturally derived constructs rooted in Hispanic and Asian cultures, respectively. Measures of these constructs have been utilized in research and found to predict delays in s...

    Authors: Jeremy NV Miles, Regina A Shih, Joan S Tucker, Annie Zhou and Elizabeth J D’Amico
    Citation: BMC Medical Research Methodology 2012 12:61
  2. The application of statistics in reported research in trauma and orthopaedic surgery has become ever more important and complex. Despite the extensive use of statistical analysis, it is still a subject which i...

    Authors: Nick R Parsons, Charlotte L Price, Richard Hiskens, Juul Achten and Matthew L Costa
    Citation: BMC Medical Research Methodology 2012 12:60
  3. Ecological or survey based methods to investigate screening uptake rates are fraught with many limitations which can be circumvented by record linkage between Census and health services datasets using variatio...

    Authors: Dermot O’Reilly, Heather Kinnear, Michael Rosato, Adrian Mairs and Clare Hall
    Citation: BMC Medical Research Methodology 2012 12:59
  4. To derive micronutrient recommendations in a scientifically sound way, it is important to obtain and analyse all published information on the association between micronutrient intake and biochemical proxies fo...

    Authors: Olga W Souverein, Carla Dullemeijer, Pieter van `t Veer and Hilko van der Voet
    Citation: BMC Medical Research Methodology 2012 12:57
  5. Prognostic factors are associated with the risk of a subsequent outcome in people with a given disease or health condition. Meta-analysis using individual participant data (IPD), where the raw data are synthes...

    Authors: Ghada Abo-Zaid, Willi Sauerbrei and Richard D Riley
    Citation: BMC Medical Research Methodology 2012 12:56
  6. For systematic reviews providing evidence for policy decisions in specific geographical regions, there is a need to minimise regional bias when seeking out relevant research studies. Studies on people’s views ...

    Authors: Claire Stansfield, Josephine Kavanagh, Rebecca Rees, Alan Gomersall and James Thomas
    Citation: BMC Medical Research Methodology 2012 12:55
  7. is an online registry of systematic reviews evaluating the effectiveness of public health interventions. Extensive searching of bibliographic databases is required to keep the registry up to...

    Authors: Edwin Lee, Maureen Dobbins, Kara DeCorby, Lyndsey McRae, Daiva Tirilis and Heather Husson
    Citation: BMC Medical Research Methodology 2012 12:51
  8. The standardisation of the assessment methodology and case definition represents a major precondition for the comparison of study results and the conduction of meta-analyses. International guidelines provide r...

    Authors: Michael Schwenk, Andreas Lauenroth, Christian Stock, Raquel Rodriguez Moreno, Peter Oster, Gretl McHugh, Chris Todd and Klaus Hauer
    Citation: BMC Medical Research Methodology 2012 12:50
  9. A method for assessing the model validity of randomised controlled trials of homeopathy is needed. To date, only conventional standards for assessing intrinsic bias (internal validity) of trials have been invo...

    Authors: Robert T Mathie, Helmut Roniger, Michel Van Wassenhoven, Joyce Frye, Jennifer Jacobs, Menachem Oberbaum, Marie-France Bordet, Chaturbhuja Nayak, Gilles Chaufferin, John A Ives, Flávio Dantas and Peter Fisher
    Citation: BMC Medical Research Methodology 2012 12:49
  10. Identification of high-risk individuals is crucial for effective implementation of type 2 diabetes mellitus prevention programs. Several studies have shown that multivariable predictive functions perform as we...

    Authors: Calvin Woon-Loong Chin, Elian Hui San Chia, Stefan Ma, Derrick Heng, Maudrene Tan, Jeanette Lee, E Shyong Tai and Agus Salim
    Citation: BMC Medical Research Methodology 2012 12:48
  11. The preliminary results of a study are usually presented as an abstract in conference meetings. The reporting quality of those abstracts and the relationship between their study designs and full paper publicat...

    Authors: Uzung Yoon and Karsten Knobloch
    Citation: BMC Medical Research Methodology 2012 12:47
  12. Multiple imputation is often used for missing data. When a model contains as covariates more than one function of a variable, it is not obvious how best to impute missing values in these covariates. Consider a...

    Authors: Shaun R Seaman, Jonathan W Bartlett and Ian R White
    Citation: BMC Medical Research Methodology 2012 12:46
  13. Non-coverage of households without a landline telephone is a major concern of telephone survey researchers. Sampling mobile telephone users in national surveys is vital in order to gain access to the growing p...

    Authors: Orla McBride, Karen Morgan and Hannah McGee
    Citation: BMC Medical Research Methodology 2012 12:45
  14. The Estonian Postmenopausal Hormone Therapy (EPHT) Trial assigned 4170 potential participants prior to recruitment to blind or non-blind hormone therapy (HT), with placebo or non-treatment the respective alter...

    Authors: Piret Veerus, Krista Fischer, Matti Hakama and Elina Hemminki
    Citation: BMC Medical Research Methodology 2012 12:44
  15. The objective of this study was to validate physical activity questionnaires for cystic fibrosis (CF) against accelerometry and cycle ergometry.

    Authors: Katharina C Ruf, Sonja Fehn, Michèle Bachmann, Alexander Moeller, Kristina Roth, Susi Kriemler and Helge Hebestreit
    Citation: BMC Medical Research Methodology 2012 12:43
  16. Chronic stress results from an imbalance of personal traits, resources and the demands placed upon an individual by social and occupational situations. This chronic stress can be measured using the Trier Inven...

    Authors: Katja Petrowski, Sören Paul, Cornelia Albani and Elmar Brähler
    Citation: BMC Medical Research Methodology 2012 12:42
  17. Physician surveys are an important tool to assess attitudes, beliefs and self-reported behaviors of this policy relevant group. In order for a physician to respond to a mailed survey, they must first open the ...

    Authors: Jeanette Y Ziegenfuss, Kelly Burmeister, Katherine M James, Lindsey Haas, Jon C Tilburt and Timothy J Beebe
    Citation: BMC Medical Research Methodology 2012 12:41
  18. Chronic obstructive pulmonary disease (COPD) is an inflammatory pulmonary disorder with systemic inflammatory manifestations that are mediated by circulating acute-phase reactants. This study compared an enzym...

    Authors: José L López-Campos, Elena Arellano, Carmen Calero, Ana Delgado, Eduardo Márquez, Pilar Cejudo, Francisco Ortega, Francisco Rodríguez-Panadero and Ana Montes-Worboys
    Citation: BMC Medical Research Methodology 2012 12:40
  19. Physical activity is an important determinant of health. Walking is the most common physical activity performed by adults and the presence of sidewalks along roads is a determinant of walking. Geographic infor...

    Authors: Ian Janssen and Andrei Rosu
    Citation: BMC Medical Research Methodology 2012 12:39
  20. Modeling childhood body mass index (BMI) trajectories, versus estimating change in BMI between specific ages, may improve prediction of later body-size-related outcomes. Prior studies of BMI trajectories are l...

    Authors: Xiaozhong Wen, Ken Kleinman, Matthew W Gillman, Sheryl L Rifas-Shiman and Elsie M Taveras
    Citation: BMC Medical Research Methodology 2012 12:38
  21. The short version of the World Health Organization's Quality of Life Instrument (WHOQOL-BREF) is widely validated and popularly used in assessing the subjective quality of life (QOL) of patients and the genera...

    Authors: Ping Xia, Ningxiu Li, Kit-Tai Hau, Chaojie Liu and Yubo Lu
    Citation: BMC Medical Research Methodology 2012 12:37
  22. Upper arm postures are believed to be an important risk determinant for musculoskeletal disorder development in the neck and shoulders. The 10th and 90th percentiles of the angular elevation distribution have bee...

    Authors: Svend Erik Mathiassen, Jens Wahlström and Mikael Forsman
    Citation: BMC Medical Research Methodology 2012 12:36
  23. Clinical trial participants may be temporarily absent or withdraw from trials, leading to missing data. In intention-to-treat (ITT) analyses, several approaches are used for handling the missing information - ...

    Authors: Jonas Ranstam, Aleksandra Turkiewicz, Steven Boonen, Jan Van Meirhaeghe, Leonard Bastian and Douglas Wardlaw
    Citation: BMC Medical Research Methodology 2012 12:35
  24. An Individual Patient Data (IPD) meta-analysis is often considered the gold-standard for synthesising survival data from clinical trials. An IPD meta-analysis can be achieved by either a two-stage or a one-sta...

    Authors: Michael J Crowther, Richard D Riley, Jan A Staessen, Jiguang Wang, Francois Gueyffier and Paul C Lambert
    Citation: BMC Medical Research Methodology 2012 12:34
  25. The summary measure approach (SMA) is sometimes the only applicable tool for the analysis of repeated measurements in medical research, especially when the number of measurements is relatively large. This stud...

    Authors: Mehrdad Vossoughi, SMT Ayatollahi, Mina Towhidi and Farzaneh Ketabchi
    Citation: BMC Medical Research Methodology 2012 12:33
  26. Using a different mode of contact on the final follow-up to survey non-respondents is an identified strategy to increase response rates. This study was designed to determine if a reminder phone call or a phone...

    Authors: Jeanette Y Ziegenfuss, Kelly R Burmeister, Ann Harris, Stefan D Holubar and Timothy J Beebe
    Citation: BMC Medical Research Methodology 2012 12:32
  27. Sample sizes for obstetrical trials are often based on the opinion of investigators about clinically important effect size. We surveyed Canadian obstetricians to investigate clinically important effect sizes r...

    Authors: Sue Ross, Jill Milne, Shannon Dwinnell, Selphee Tang and Stephen Wood
    Citation: BMC Medical Research Methodology 2012 12:31
  28. Estimates of the prevalence of transmitted HIV drug resistance (TDR) in a population are derived from resistance tests performed on samples from patients thought to be naïve to antiretroviral treatment (ART). ...

    Authors: Hannah Castro, Deenan Pillay, Caroline Sabin and David T Dunn
    Citation: BMC Medical Research Methodology 2012 12:30
  29. Multicenter study designs have several advantages, but the possibility of non-random measurement error resulting from procedural differences between the centers is a special concern. While it is possible to ad...

    Authors: Lauren B Guthrie, Emily Oken, Jonathan AC Sterne, Matthew W Gillman, Rita Patel, Konstantin Vilchuck, Natalia Bogdanovich, Michael S Kramer and Richard M Martin
    Citation: BMC Medical Research Methodology 2012 12:29
  30. Marginal and multilevel logistic regression methods can estimate associations between hospital-level factors and patient-level 30-day mortality outcomes after cardiac surgery. However, it is not widely underst...

    Authors: Masoumeh Sanagou, Rory Wolfe, Andrew Forbes and Christopher Michael Reid
    Citation: BMC Medical Research Methodology 2012 12:28
  31. Blood pressure is considered to be a leading example of a valid surrogate endpoint. The aims of this study were to (i) formally evaluate systolic and diastolic blood pressure reduction as a surrogate endpoint ...

    Authors: Marissa N Lassere, Kent R Johnson, Michal Schiff and David Rees
    Citation: BMC Medical Research Methodology 2012 12:27
  32. Different types of devices are available and the choice about which to use depends on various factors: cost, physical characteristics, performance, and the validity and intra- and interinstrument reliability. ...

    Authors: Jérémy Vanhelst, Laurent Béghin, Alain Duhamel, Patrick Bergman, Michael Sjöström and Frédéric Gottrand
    Citation: BMC Medical Research Methodology 2012 12:26
  33. A special challenge for research studies of breast cancer among females is low patient participation rates. We compiled this systematic review to identify reasons why women with, or at high risk of, breast can...

    Authors: Gero Luschin, Marion Habersack and Irmina-Anna Gerlich
    Citation: BMC Medical Research Methodology 2012 12:25
  34. The weighted estimators generally used for analyzing case-cohort studies are not fully efficient and naive estimates of the predictive ability of a model from case-cohort data depend on the subcohort size. How...

    Authors: Helena Marti, Laure Carcaillon and Michel Chavance
    Citation: BMC Medical Research Methodology 2012 12:24
  35. Several methodological issues with non-randomized comparative clinical studies have been raised, one of which is whether the methods used can adequately identify uncertainties that evolve dynamically with time...

    Authors: Darong Wu, Yefeng Cai, Jianxiong Cai, Qiuli Liu, Yuanqi Zhao, Jingheng Cai, Min Zhao, Yonghui Huang, Liuer Ye, Yubo Lu and Xianping Guo
    Citation: BMC Medical Research Methodology 2012 12:23
  36. Asthma is among the most common chronic diseases in working-aged populations and occupational exposures are important causal agents. Our aims were to evaluate the best methods to assess occurrence, public heal...

    Authors: Maritta S Jaakkola and Jouni JK Jaakkola
    Citation: BMC Medical Research Methodology 2012 12:22
  37. Single-item physical activity questions provide a quick approximation of physical activity levels. While recall questionnaires provide a more detailed picture of an individual's level of physical activity, sin...

    Authors: Dawn P Gill, Gareth R Jones, Guangyong Zou and Mark Speechley
    Citation: BMC Medical Research Methodology 2012 12:20
  38. Patient Safety Indicators (PSI) are being modestly used in Spain, somewhat due to concerns on their empirical properties. This paper provides evidence by answering three questions: a) Are PSI differences acros...

    Authors: Enrique Bernal-Delgado, Sandra García-Armesto, Natalia Martínez-Lizaga, Begoña Abadía-Taira, Joaquín Beltrán-Peribañez and Salvador Peiró
    Citation: BMC Medical Research Methodology 2012 12:19
  39. Patient's knowledge on diabetes, hypertension and hyperlipidaemia and its medications can be used as one of the outcome measures to assess the effectiveness of educational intervention. To date, no such instru...

    Authors: Pauline SM Lai, Siew Siang Chua, Ching Hooi Tan and Siew Pheng Chan
    Citation: BMC Medical Research Methodology 2012 12:18
  40. Chronic Obstructive Pulmonary Disease (COPD) is currently the fifth leading cause of death in Australia, and there are marked differences in mortality trends between men and women. In this study, we have sough...

    Authors: Bircan Erbas, Shahid Ullah, Rob J Hyndman, Michelle Scollo and Michael Abramson
    Citation: BMC Medical Research Methodology 2012 12:17
  41. Graphical models were identified as a promising new approach to modeling high-dimensional clinical data. They provided a probabilistic tool to display, analyze and visualize the net-like dependence structures ...

    Authors: Ralf Strobl, Eva Grill and Ulrich Mansmann
    Citation: BMC Medical Research Methodology 2012 12:16
  42. A discrete choice experiment (DCE) is a preference survey which asks participants to make a choice among product portfolios comparing the key product characteristics by performing several choice tasks. Analyzi...

    Authors: Ji Cheng, Eleanor Pullenayegum, Deborah A Marshall, John K Marshall and Lehana Thabane
    Citation: BMC Medical Research Methodology 2012 12:15
  43. Research on the effect of survey timing on patient-reported experiences and patient satisfaction with health services has produced contradictory results. The objective of this study was thus to assess the asso...

    Authors: Oyvind A Bjertnaes
    Citation: BMC Medical Research Methodology 2012 12:13
  44. Before a new test is introduced in clinical practice, evidence is needed to demonstrate that its use will lead to improvements in patient health outcomes. Studies reporting test accuracy may not be sufficient,...

    Authors: Lukas P Staub, Sarah J Lord, R John Simes, Suzanne Dyer, Nehmat Houssami, Robert YM Chen and Les Irwig
    Citation: BMC Medical Research Methodology 2012 12:12
  45. The European Centres of Reference Network for Cystic Fibrosis (ECORN-CF) established an Internet forum which provides the opportunity for CF patients and other interested people to ask experts questions about ...

    Authors: Daniela d'Alquen, Kris De Boeck, Judy Bradley, Věra Vávrová, Birgit Dembski, Thomas OF Wagner, Annette Pfalz and Helge Hebestreit
    Citation: BMC Medical Research Methodology 2012 12:11

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