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  1. Healthcare delivery is largely accomplished in and through conversations between people, and healthcare quality and effectiveness depend enormously upon the communication practices employed within these conver...

    Authors: Ruth H Parry and Victoria Land
    Citation: BMC Medical Research Methodology 2013 13:69
    Content type: Correspondence Published on:

  2. The ability to accurately forecast census counts in hospital departments has considerable implications for hospital resource allocation. In recent years several different methods have been proposed forecasting...

    Authors: Devin C Koestler, Hernando Ombao and Jesse Bender
    Citation: BMC Medical Research Methodology 2013 13:67
    Content type: Research article Published on:

  3. Statistical process control (SPC), an industrial sphere initiative, has recently been applied in health care and public health surveillance. SPC methods assume independent observations and process autocorrelat...

    Authors: John L Moran and Patricia J Solomon
    Citation: BMC Medical Research Methodology 2013 13:66
    Content type: Research article Published on:

  4. In medical informatics, psychology, market research and many other fields, researchers often need to analyze and model ranking data. However, there is no statistical software that provides tools for the compre...

    Authors: Paul H Lee and Philip LH Yu
    Citation: BMC Medical Research Methodology 2013 13:65
    Content type: Software Published on:

  5. The Pathobiology of Prediabetes in A Biracial Cohort study is a prospective evaluation of the transition from normal to impaired glucose regulation among African American and Caucasian adults with parental typ...

    Authors: Sotonte Ebenibo, Chimaroke Edeoga, Ann Ammons, Nonso Egbuonu and Samuel Dagogo-Jack
    Citation: BMC Medical Research Methodology 2013 13:64
    Content type: Research article Published on:

  6. The quality of a consultation provided by a physician can have a profound impact on the quality of care and patient engagement in treatment decisions. When the COPD Assessment Test (CAT) was developed, one of ...

    Authors: Kevin Gruffydd-Jones, Helen Marsden, Steve Holmes, Peter Kardos, Roger Escamilla, Roberto Dal Negro, June Roberts, Gilbert Nadeau, David Leather and Paul Jones
    Citation: BMC Medical Research Methodology 2013 13:63
    Content type: Correspondence Published on:

  7. To optimize the planning of blood donations but also to continue motivating the volunteers it is important to streamline the practical organization of the timing of donations. While donors are asked to return ...

    Authors: Kazem Nasserinejad, Wim de Kort, Mireille Baart, Arnošt Komárek, Joost van Rosmalen and Emmanuel Lesaffre
    Citation: BMC Medical Research Methodology 2013 13:62
    Content type: Research article Published on:

  8. Rater agreement is important in clinical research, and Cohen’s Kappa is a widely used method for assessing inter-rater reliability; however, there are well documented statistical problems associated with the m...

    Authors: Nahathai Wongpakaran, Tinakon Wongpakaran, Danny Wedding and Kilem L Gwet
    Citation: BMC Medical Research Methodology 2013 13:61
    Content type: Research article Published on:

  9. Models of hepatitis C virus (HCV) kinetics are increasingly used to estimate and to compare in vivo drug’s antiviral effectiveness of new potent anti-HCV agents. Viral kinetic parameters can be estimated using no...

    Authors: Cédric Laouénan, Jeremie Guedj and France Mentré
    Citation: BMC Medical Research Methodology 2013 13:60
    Content type: Research article Published on:

  10. The study describes the methodological challenges encountered in an observational study estimating the effectiveness of colonoscopy in reducing colorectal cancer (CRC) incidence and mortality.

    Authors: Binu J Jacob, Rinku Sutradhar, Rahim Moineddin, Nancy N Baxter and David R Urbach
    Citation: BMC Medical Research Methodology 2013 13:59
    Content type: Research article Published on:

  12. Using covariance or mean estimates from previous data introduces randomness into each power value in a power curve. Creating confidence intervals about the power estimates improves study planning by allowing s...

    Authors: Matthew J Gribbin, Yueh-Yun Chi, Paul W Stewart and Keith E Muller
    Citation: BMC Medical Research Methodology 2013 13:57
    Content type: Research article Published on:

  13. Birth cohort studies, where parents consent for their child to be enrolled in a longitudinal study prior to or soon after birth, are a powerful study design in epidemiology and developmental research. Particip...

    Authors: Patricia J Lucas, Debra Allnock and Tricia Jessiman
    Citation: BMC Medical Research Methodology 2013 13:56
    Content type: Research article Published on:

  14. The role of the clinical nurse/midwife specialist and advanced nurse/midwife practitioner is complex not least because of the diversity in how the roles are operationalised across health settings and within mu...

    Authors: Joan G Lalor, Dympna Casey, Naomi Elliott, Imelda Coyne, Catherine Comiskey, Agnes Higgins, Kathy Murphy, Declan Devane and Cecily Begley
    Citation: BMC Medical Research Methodology 2013 13:55
    Content type: Research article Published on:

  15. The editors of BMC Medical Research Methodology would like to thank all our reviewers who have contributed to the journal in Volume 12 (2012).

    Authors: Adrian Aldcroft
    Citation: BMC Medical Research Methodology 2013 13:45
    Content type: Reviewer acknowledgement Published on:

  16. Static posture, repetitive movements and lack of physical variation are known risk factors for work-related musculoskeletal disorders, and thus needs to be properly assessed in occupational studies. The aims o...

    Authors: Afshin Samani, Svend Erik Mathiassen and Pascal Madeleine
    Citation: BMC Medical Research Methodology 2013 13:54
    Content type: Research article Published on:

  17. Accelerometer cutpoints based on absolute intensity may under or overestimate levels of physical activity due to the lack of consideration for an individual’s current fitness level. The purpose of this study w...

    Authors: Cemal Ozemek, Heather L Cochran, Scott J Strath, Wonwoo Byun and Leonard A Kaminsky
    Citation: BMC Medical Research Methodology 2013 13:53
    Content type: Research article Published on:

  19. Discordance between dialysis registry and death certificate reported death has been demonstrated. Since cause of death is measured using registry data in dialysis patients and death certificate data in the gen...

    Authors: Jean-Philippe Lafrance, Elham Rahme, Sameena Iqbal, Martine Leblanc, Vincent Pichette, Naoual Elftouh and Michel Vallée
    Citation: BMC Medical Research Methodology 2013 13:51
    Content type: Research article Published on:

  20. A systematic review, with or without a meta-analysis, should be undertaken to determine if the research question of interest has already been answered before a new trial begins. There has been limited research...

    Authors: Ashley P Jones, Elizabeth Conroy, Paula R Williamson, Mike Clarke and Carrol Gamble
    Citation: BMC Medical Research Methodology 2013 13:50
    Content type: Research article Published on:

  21. In recent years response rates on telephone surveys have been declining. Rates for the behavioral risk factor surveillance system (BRFSS) have also declined, prompting the use of new methods of weighting and t...

    Authors: Carol Pierannunzi, Shaohua Sean Hu and Lina Balluz
    Citation: BMC Medical Research Methodology 2013 13:49
    Content type: Research article Published on:

  22. Scoping studies are increasingly common for broadly searching the literature on a specific topic, yet researchers lack an agreed-upon definition of and framework for the methodology. In 2005, Arksey and O’Mall...

    Authors: Helena ML Daudt, Catherine van Mossel and Samantha J Scott
    Citation: BMC Medical Research Methodology 2013 13:48
    Content type: Debate Published on:

  23. Assessment of disagreement among multiple measurements for the same subject by different observers remains an important problem in medicine. Several measures have been applied to assess observer agreement. How...

    Authors: Teresa Henriques, Luis Antunes, João Bernardes, Mara Matias, Diogo Sato and Cristina Costa-Santos
    Citation: BMC Medical Research Methodology 2013 13:47
    Content type: Research article Published on:

  24. Studies that systematically search for and synthesise qualitative research are becoming more evident in health care, and they can make an important contribution to patient care. However, there is still no agre...

    Authors: Francine Toye, Kate Seers, Nick Allcock, Michelle Briggs, Eloise Carr, JoyAnn Andrews and Karen Barker
    Citation: BMC Medical Research Methodology 2013 13:46
    Content type: Research article Published on:

  25. Subjects with breast cancer enrolled in trials may experience multiple events such as local recurrence, distant recurrence or death. These events are not independent; the occurrence of one may increase the ris...

    Authors: Sameer Parpia, Lehana Thabane, Jim A Julian, Timothy J Whelan and Mark N Levine
    Citation: BMC Medical Research Methodology 2013 13:44
    Content type: Research article Published on:

  26. Functional data analysis (FDA) is increasingly being used to better analyze, model and predict time series data. Key aspects of FDA include the choice of smoothing technique, data reduction, adjustment for clu...

    Authors: Shahid Ullah and Caroline F Finch
    Citation: BMC Medical Research Methodology 2013 13:43
    Content type: Research article Published on:

  27. Many prognostic models have been developed. Different types of models, i.e. prognostic factor and outcome prediction studies, serve different purposes, which should be reflected in how the results are summariz...

    Authors: Tobias van den Berg, Martijn W Heymans, Stephanie S Leone, David Vergouw, Jill A Hayden, Arianne P Verhagen and Henrica CW de Vet
    Citation: BMC Medical Research Methodology 2013 13:42
    Content type: Research article Published on:

  28. Telephone surveys based on samples of landline telephone numbers are widely used to measure the prevalence of health risk behaviours such as smoking, drug use and alcohol consumption. An increasing number of h...

    Authors: Michael Livingston, Paul Dietze, Jason Ferris, Darren Pennay, Linda Hayes and Simon Lenton
    Citation: BMC Medical Research Methodology 2013 13:41
    Content type: Research article Published on:

  29. Evaluating large-scale disease management interventions implemented in actual health care settings is a complex undertaking for which universally accepted methods do not exist. Fundamental issues, such as a la...

    Authors: Arianne MJ Elissen, John L Adams, Marieke Spreeuwenberg, Inge GP Duimel-Peeters, Cor Spreeuwenberg, Ariel Linden and Hubertus JM Vrijhoef
    Citation: BMC Medical Research Methodology 2013 13:40
    Content type: Research article Published on:

  30. Estimating harm rates for specific patient populations and detecting significant changes in them over time are essential if patient safety in general practice is to be improved. Clinical record review (CRR) is...

    Authors: Carl de Wet, Paul Johnson, Catherine O’Donnell and Paul Bowie
    Citation: BMC Medical Research Methodology 2013 13:39
    Content type: Research article Published on:

  31. Self-reported weight and height is frequently used to quantify overweight and obesity. It is however, associated with limitations such as bias and poor agreement, which may be a result of social desirability o...

    Authors: Sze Lin Yoong, Mariko Leanne Carey, Catherine D’Este and Robert William Sanson-Fisher
    Citation: BMC Medical Research Methodology 2013 13:38
    Content type: Research article Published on:

  32. Following publication of the first worked example of the “best fit” method of evidence synthesis for the systematic review of qualitative evidence in this journal, the originators of the method identified a ne...

    Authors: Christopher Carroll, Andrew Booth, Joanna Leaviss and Jo Rick
    Citation: BMC Medical Research Methodology 2013 13:37
    Content type: Correspondence Published on:

  33. Life expectancy is of increasing prime interest for a variety of reasons. In many countries, life expectancy is growing linearly, without any indication of reaching a limit. The state of North Rhine–Westphalia...

    Authors: Dankmar Böhning, Sarah Karasek, Claudia Terschüren, Rolf Annuß and Rainer Fehr
    Citation: BMC Medical Research Methodology 2013 13:36
    Content type: Research article Published on:

  34. In network meta-analyses, several treatments can be compared by connecting evidence from clinical trials that have investigated two or more treatments. The resulting trial network allows estimating the relativ...

    Authors: Ulrike Krahn, Harald Binder and Jochem König
    Citation: BMC Medical Research Methodology 2013 13:35
    Content type: Research article Published on:

  37. Estimating the incidence of medical conditions using claims data often requires constructing a prevalence period that predates an event of interest, for instance the diagnosis of cancer, to exclude those with ...

    Authors: Robert I Griffiths, Cynthia D O’Malley, Robert J Herbert and Mark D Danese
    Citation: BMC Medical Research Methodology 2013 13:32
    Content type: Research article Published on:

  38. Participation bias is a well-known phenomenon in epidemiologic research, where individuals consenting to research studies differ from individuals who are not able or willing to participate. These dissimilariti...

    Authors: Janet Raboud, DeSheng Su, Ann N Burchell, Sandra Gardner, Sharon Walmsley, Ahmed M Bayoumi, Sandra Blitz, Curtis Cooper, Irving Salit, Jeff Cohen, Sean B Rourke and Mona R Loutfy
    Citation: BMC Medical Research Methodology 2013 13:31
    Content type: Research article Published on:

  39. In Germany, hospitals can deliver data from patients with pelvic fractures selectively or twofold to two different trauma registries, i.e. the German Pelvic Injury Register (PIR) and the TraumaRegister DGU® (T...

    Authors: Markus Burkhardt, Ulrike Nienaber, Joerg H Holstein, Ulf Culemann, Bertil Bouillon, Emin Aghayev, Thomas Paffrath, Marc Maegele, Tim Pohlemann and Rolf Lefering
    Citation: BMC Medical Research Methodology 2013 13:30
    Content type: Research article Published on:

  40. Immunological correlates of protection are biological markers such as disease-specific antibodies which correlate with protection against disease and which are measurable with immunological assays. It is commo...

    Authors: Xuan Chen, Fabrice Bailleux, Kamal Desai, Li Qin and Andrew J Dunning
    Citation: BMC Medical Research Methodology 2013 13:29
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Medical Research Methodology 2017 17:19

  41. The Center for Epidemiologic Studies - Depression scale (CES-D) is a validated tool commonly used to screen depressive symptoms. As with any self-administered questionnaire, missing data are frequently observe...

    Authors: Noémie Resseguier, Hélène Verdoux, Roch Giorgi, Françoise Clavel-Chapelon and Xavier Paoletti
    Citation: BMC Medical Research Methodology 2013 13:28
    Content type: Research article Published on:

  42. Within longitudinal epidemiological research, ‘count’ outcome variables with an excess of zeros frequently occur. Although these outcomes are frequently analysed with a linear mixed model, or a Poisson mixed m...

    Authors: Alette S Spriensma, Tibor RS Hajos, Michiel R de Boer, Martijn W Heymans and Jos WR Twisk
    Citation: BMC Medical Research Methodology 2013 13:27
    Content type: Research article Published on:

  43. The occurrence of communicable diseases (CD) depends on exposure to contagious persons. The effects of exposure to CD are delayed in time and contagious persons remain contagious for several days during which ...

    Authors: Cécile Payet, Nicolas Voirin, Philippe Vanhems and René Ecochard
    Citation: BMC Medical Research Methodology 2013 13:26
    Content type: Research article Published on:

  45. When calculating the number of deaths attributable to alcohol consumption (i.e., the number of deaths that would not have occurred if everyone was a lifetime abstainer), alcohol consumption is most often model...

    Authors: Gerrit Gmel, Kevin D Shield, Tara AK Kehoe-Chan and Jürgen Rehm
    Citation: BMC Medical Research Methodology 2013 13:24
    Content type: Research article Published on:

  46. Little evidence is available for the validity of dietary fish and polyunsaturated fatty acid intake derived from interviewer-administered questionnaires and plasma docosahexaenoic acid (DHA) and eicosapentaeno...

    Authors: Kuo-Liong Chien, Meei-Shyuan Lee, Yi-Tsen Tsai, Pey-Rong Chen, Hung-Ju Lin, Hsiu-Ching Hsu, Yuan-The Lee and Ming-Fong Chen
    Citation: BMC Medical Research Methodology 2013 13:23
    Content type: Research article Published on:

  47. Diabetes–related lower limb amputations are associated with considerable morbidity and mortality and are usually preceded by foot ulceration. The available systematic reviews of aggregate data are compromised ...

    Authors: Fay Crawford, Chantelle Anandan, Francesca M Chappell, Gordon D Murray, Jacqueline F Price, Aziz Sheikh, Colin R Simpson, Martin Maxwell, Gerard P Stansby, Matthew J Young, Caroline A Abbott, Andrew JM Boulton, Edward J Boyko, Thomas Kastenbauer, Graham P Leese, Matteo Monami…
    Citation: BMC Medical Research Methodology 2013 13:22
    Content type: Study protocol Published on:

  48. Interaction in clinical trials presents challenges for design and appropriate sample size estimation. Here we considered interaction between treatment assignment and a dichotomous prognostic factor with a cont...

    Authors: William M Reichmann, Michael P LaValley, David R Gagnon and Elena Losina
    Citation: BMC Medical Research Methodology 2013 13:21
    Content type: Research article Published on:

  49. Multiple sclerosis (MS), a common neurodegenerative disease, has well-described associations with quality of life (QoL) impairment. QoL changes found in longitudinal studies are difficult to interpret due to t...

    Authors: Mohamed Boucekine, Anderson Loundou, Karine Baumstarck, Patricia Minaya-Flores, Jean Pelletier, Badih Ghattas and Pascal Auquier
    Citation: BMC Medical Research Methodology 2013 13:20
    Content type: Research article Published on:

  50. Case-control studies are generally designed to investigate the effect of exposures on the risk of a disease. Detailed information on past exposures is collected at the time of study. However, only the cumulate...

    Authors: Héloïse Gauvin, Aude Lacourt and Karen Leffondré
    Citation: BMC Medical Research Methodology 2013 13:18
    Content type: Technical advance Published on:
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