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BMC Medical Research Methodology

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  1. Content type: Research article

    Vision influences functioning and disability of children with cerebral palsy, so there is a growing need for psychometrically robust tools to advance assessment of children’s vision abilities in clinical pract...

    Authors: Belinda Deramore Denver, Margareta Adolfsson, Elspeth Froude, Peter Rosenbaum and Christine Imms

    Citation: BMC Medical Research Methodology 2017 17:46

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  2. Content type: Research article

    Mediation is an important issue considered in the behavioral, medical, and social sciences. It addresses situations where the effect of a predictor variable X on an outcome variable Y is explained to some extent ...

    Authors: George J. Knafl, Kathleen A. Knafl, Margaret Grey, Jane Dixon, Janet A. Deatrick and Agatha M. Gallo

    Citation: BMC Medical Research Methodology 2017 17:45

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  3. Content type: Research article

    Meta-analysis is very useful to summarize the effect of a treatment or a risk factor for a given disease. Often studies report results based on log-transformed variables in order to achieve the principal assum...

    Authors: Miguel Rodríguez-Barranco, Aurelio Tobías, Daniel Redondo, Elena Molina-Portillo and María José Sánchez

    Citation: BMC Medical Research Methodology 2017 17:44

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    The Erratum to this article has been published in BMC Medical Research Methodology 2017 17:91

  4. Content type: Correspondence

    With the increasing implementation of web-based, mobile health interventions in clinical trials, it is crucial for researchers to address the security and privacy concerns of patient information according to h...

    Authors: Roy Eagleson, Luis Altamirano-Diaz, Alex McInnis, Eva Welisch, Stefanie De Jesus, Harry Prapavessis, Meghan Rombeek, Jamie A. Seabrook, Teresa Park and Kambiz Norozi

    Citation: BMC Medical Research Methodology 2017 17:43

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  5. Content type: Research article

    Propensity scores are typically applied in retrospective cohort studies. We describe the feasibility of matching on a propensity score derived from a retrospective cohort and subsequently applied in a prospect...

    Authors: Eric S. Johnson, John F. Dickerson, William M. Vollmer, Alee M. Rowley, Cheryl Ritenbaugh, Richard A. Deyo and Lynn DeBar

    Citation: BMC Medical Research Methodology 2017 17:42

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  6. Content type: Research article

    Reporting of adverse events in randomized clinical trials (RCTs) is encouraged by the authors of The Consolidated Standards of Reporting Trials (CONSORT) statement. With robust methodological design and adequa...

    Authors: Lindsay M. Gorrell, Roger M. Engel, Reidar P. Lystad and Benjamin T. Brown

    Citation: BMC Medical Research Methodology 2017 17:41

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  7. Content type: Research article

    Sample selection can substantially affect the solutions generated using exploratory factor analysis. Validation studies of the 12-item World Health Organization (WHO) Disability Assessment Schedule 2.0 (WHODAS...

    Authors: Cadeyrn J. Gaskin, Sylvie D. Lambert, Steven J. Bowe and Liliana Orellana

    Citation: BMC Medical Research Methodology 2017 17:40

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  8. Content type: Research article

    Most meta-analyses in systematic reviews, including Cochrane ones, do not have sufficient statistical power to detect or refute even large intervention effects. This is why a meta-analysis ought to be regarded...

    Authors: Jørn Wetterslev, Janus Christian Jakobsen and Christian Gluud

    Citation: BMC Medical Research Methodology 2017 17:39

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  9. Content type: Research article

    Proliferation of terms describing the science of effectively promoting and supporting the use of research evidence in healthcare policy and practice has hampered understanding and development of the field. To ...

    Authors: Peter Bragge, Jeremy M. Grimshaw, Cynthia Lokker and Heather Colquhoun

    Citation: BMC Medical Research Methodology 2017 17:38

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  10. Content type: Research article

    The aim was to review the literature to identify the most effective methods for creating a representative sample of refugee and asylum seeker groups living in the community to participate in health and mental ...

    Authors: Joanne C. Enticott, Frances Shawyer, Shiva Vasi, Kimberly Buck, I-Hao Cheng, Grant Russell, Ritsuko Kakuma, Harry Minas and Graham Meadows

    Citation: BMC Medical Research Methodology 2017 17:37

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  11. Content type: Research article

    The development of Electronic Health Records (EHRs) in hospitals offers the ability to reuse data from patient care activities for clinical research. EHR4CR is a European public-private partnership aiming to d...

    Authors: Yannick Girardeau, Justin Doods, Eric Zapletal, Gilles Chatellier, Christel Daniel, Anita Burgun, Martin Dugas and Bastien Rance

    Citation: BMC Medical Research Methodology 2017 17:36

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  12. Content type: Research article

    The most rigorous method for evaluating the effectiveness of diagnostic tests is through randomised trials that compare test-treatment interventions: complex interventions comprising episodes of testing, decis...

    Authors: Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Sian Taylor-Phillips, Clare Davenport, Chris Hyde and Jonathan J. Deeks

    Citation: BMC Medical Research Methodology 2017 17:32

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  13. Content type: Research article

    There is a growing recognition for the need to expand our evidence base for the clinical effectiveness of diagnostic tests. Many international bodies are calling for diagnostic randomized controlled trials to ...

    Authors: Lavinia Ferrante di Ruffano, Jacqueline Dinnes, Alice J. Sitch, Chris Hyde and Jonathan J. Deeks

    Citation: BMC Medical Research Methodology 2017 17:35

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  14. Content type: Research Article

    When developing risk models for binary data with small or sparse data sets, the standard maximum likelihood estimation (MLE) based logistic regression faces several problems including biased or infinite estima...

    Authors: M. Shafiqur Rahman and Mahbuba Sultana

    Citation: BMC Medical Research Methodology 2017 17:33

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  15. Content type: Research article

    In a new influenza pandemic, travel data such as arrival times of cases seeded by the originating country can be regarded as a combination of the epidemic size and the mobility networks of infections connectin...

    Authors: Ka Chun Chong, Benny Chung Ying Zee and Maggie Haitian Wang

    Citation: BMC Medical Research Methodology 2017 17:31

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  16. Content type: Research article

    There is a need for improving cohort retention in longitudinal studies. Our objective was to identify cohort retention strategies and implementation approaches used in studies with high retention rates.

    Authors: Martha Abshire, Victor D. Dinglas, Maan Isabella A. Cajita, Michelle N. Eakin, Dale M. Needham and Cheryl Dennison Himmelfarb

    Citation: BMC Medical Research Methodology 2017 17:30

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  17. Content type: Research article

    In the two-stage randomised trial design, a randomly sampled subset of study participants are permitted to choose their own treatment, while the remaining participants are randomised to treatment in the usual ...

    Authors: Stephen D. Walter, Robin M. Turner, Petra Macaskill, Kirsten J. McCaffery and Les Irwig

    Citation: BMC Medical Research Methodology 2017 17:29

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  18. Content type: Research article

    Individual patient data meta-analyses (IPD-MA) are often performed using a one-stage approach-- a form of generalized linear mixed model (GLMM) for binary outcomes. We compare (i) one-stage to two-stage approa...

    Authors: Doneal Thomas, Robert Platt and Andrea Benedetti

    Citation: BMC Medical Research Methodology 2017 17:28

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  19. Content type: Research Article

    Information and theory beyond copula concepts are essential to understand the dependence relationship between several marginal covariates distributions. In a therapeutic trial data scheme, most of the time, ce...

    Authors: Charles Fontaine, Jean-Pierre Daurès and Paul Landais

    Citation: BMC Medical Research Methodology 2017 17:27

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  20. Content type: Research article

    In spite of efforts to employ risk-based strategies to increase monitoring efficiency in the academic setting, empirical evidence on their effectiveness remains sparse. This mixed-methods study aimed to evalua...

    Authors: Belinda von Niederhäusern, Annette Orleth, Sabine Schädelin, Nawal Rawi, Martin Velkopolszky, Claudia Becherer, Pascal Benkert, Priya Satalkar, Matthias Briel and Christiane Pauli-Magnus

    Citation: BMC Medical Research Methodology 2017 17:26

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  21. Content type: Research article

    Observational studies are widely used in pharmacoepidemiology. Several designs can be used, in particular self-controlled designs (case-crossover and self-controlled case series). These designs offer the advan...

    Authors: Nathalie Gault, Johann Castañeda-Sanabria, Yann De Rycke, Sylvie Guillo, Stéphanie Foulon and Florence Tubach

    Citation: BMC Medical Research Methodology 2017 17:25

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  22. Content type: Research article

    Linkage of administrative data sources often relies on probabilistic methods using a set of common identifiers (e.g. sex, date of birth, postcode). Variation in data quality on an individual or organisational ...

    Authors: Katie Harron, Gareth Hagger-Johnson, Ruth Gilbert and Harvey Goldstein

    Citation: BMC Medical Research Methodology 2017 17:23

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  23. Content type: Research article

    Multiple barriers may inhibit the adoption of clinical interventions and impede successful implementation. Use of standardised methods to prioritise barriers to target when selecting implementation interventio...

    Authors: Louise E. Craig, Leonid Churilov, Liudmyla Olenko, Dominique A. Cadilhac, Rohan Grimley, Simeon Dale, Cintia Martinez-Garduno, Elizabeth McInnes, Julie Considine, Jeremy M. Grimshaw and Sandy Middleton

    Citation: BMC Medical Research Methodology 2017 17:24

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  24. Content type: Research article

    Within epidemiological and clinical research, missing data are a common issue and often over looked in publications. When the issue of missing observations is addressed it is usually assumed that the missing d...

    Authors: M. Smuk, J. R. Carpenter and T. P. Morris

    Citation: BMC Medical Research Methodology 2017 17:21

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    The Erratum to this article has been published in BMC Medical Research Methodology 2017 17:51

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